Senior Scientist, Molecular Biology ADC

Eli Lilly and CompanyBoston, MA
1d

About The Position

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for motivated individuals who are determined to make life better for people around the world. Verve Therapeutics, a wholly owned subsidiary of Eli Lilly, is created with a singular focus: to protect the world from heart disease. Founded by world-leading experts in cardiovascular medicine, human genetics and gene-editing, the company aims to develop transformative, once-and-done therapies for coronary heart disease. Verve’s gene editing medicines are designed to safely edit the genome of adults and mimic naturally occurring gene variants to permanently lower LDL cholesterol and triglyceride levels. In this role, you will be part of a diverse team of scientists delivering product and process understanding to deliver the antibody-drug conjugate portfolio. Ideal candidates will possess experience across multiple analytical techniques, demonstrate an aptitude in technical problem solving, and be motivated to work both independently and collaboratively in a dynamic environment. The ideal candidate will demonstrate learning agility and be able to work with cross-functional teams.

Requirements

  • BS or MS in Biochemistry, Chemistry, Biology, Molecular Biology or Biotechnology or a related field and 3-7 years of pharmaceutical industry experience
  • Experience with the development and execution of characterization assays for gene therapy drug substances and drug products.
  • Experience with method validation and transfer.
  • Effective oral and written communication skills.
  • The ability to work productively in an interdisciplinary team environment.
  • Ability to balance multiple activities, prioritize and handle ambiguity.
  • Qualified applicants must be authorized to work in the United States on a full-time basis. Lilly will not provide support for or sponsor work authorization or visas for this role, including but not limited to F-1 CPT, F-1 OPT, F-1 STEM OPT, J-1, H-1B, TN, O-1, E-3, H-1B1, or L-1

Nice To Haves

  • Demonstration of scientific and people leadership skills.

Responsibilities

  • Develop analytical methods to support progression of the gene therapy portfolio.
  • Evaluate and/or implement new analytical technologies/methods to advance Lilly's current analytical capabilities for bioproduct testing with a focus on state-of-the-art separation sciences capabilities.
  • Hands-on experience designing, developing and executing assays for oligonucleotide analysis including: qPCR/dPCR and RT-qPCR.
  • Generate key data and information applying qPCR, ELISA, gel electrophoresis and/or other analysis techniques.
  • Engage with scientists across Eli Lilly’s Development and Manufacturing organizations to develop and validate robust analytical methods
  • Identify and exploit new scientific concepts, strong problem-solving skills, and be self-motivated to contribute across multiple projects
  • Strong written and verbal communication to speak to both technical and business-related implications of your work.

Benefits

  • employees also will be eligible for a company bonus (depending, in part, on company and individual performance).
  • Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).
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