Senior Scientist, In Vivo Pharmacology

City Therapeutics • Cambridge, MA

68d • $136,000 - $154,000

About The Position

The Senior Scientist, In Vivo Pharmacology will play a key role in developing mouse and/or rat models of CNS disease and screening potential RNAi-based therapeutics in the CNS space. The Scientist will be responsible for designing and executing experiments and working collaboratively with the Biology, Platform, and Chemistry teams.

Requirements

• PhD plus 2-3 years’ experience (or equivalent) working in the CNS space. Experience in industry or drug-discovery is preferred.
• Strong knowledge of CNS biology and disease models.
• Ability to perform Intravenous, Intrathecal, Intra-Cisterna Magna, and/or Intracerebroventricular injections in rats and/or mice.
• Ability to perform brain dissections and isolate different parts of the brain for analysis
• Ability to work collaboratively in a multi-team environment.
• Ability to perform ex vivo analysis of tissues (RT-qPCR, western blot, ELISA)
• Strong record-keeping and presentation skills.

Responsibilities

• Design and execute in vivo experiments in the CNS space
• Lead the development of mouse and/or rat models of CNS disease
• Screen potential therapeutics in vivo
• Represent the In Vivo Pharmacology team in program team meetings
• Work collaboratively with programs leads and representatives from other teams
• Present findings in program team meetings and in company-wide meetings

Benefits

• medical
• dental
• vision
• life insurance
• health and dependent care FSA accounts
• HSA/HRA accounts with company contributions
• 401(k) with competitive company match

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: Ph.D. or professional degree
• Number of Employees: 11-50 employees