Senior Scientist I, Clinical Biomarker Development
About The Position
Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: The Senior Scientist I in Clinical Biomarker Development team, within the Translational Medicine will play a key role in the design, execution, and interpretation of clinical biomarker strategies across Revolution Medicine’s oncology pipeline.
Requirements
- PhD in a relevant scientific discipline with 3+ years of relevant industry experience in clinical biomarkers, translational medicine, or related roles.
- Experience supporting oncology clinical trials with biomarker components.
- Familiarity with biomarker platforms such as genomic/molecular and proteomic assays.
- Experience working with CROs and managing external vendors.
- Strong scientific communication skills and ability to work cross-functionally.
Nice To Haves
- Experience with targeted oncology therapies or RAS/MAPK pathway biology.
- Biological understanding of pancreatic, non small cell lung and/or colorectal cancers is preferred.
- Familiarity with analytical software for data anlaysis and interpretation.
Responsibilities
- Design and execute clinical biomarker strategies to support early response monitoring, patient stratification, and understanding resistance mechanisms.
- Support biomarker implementation for early- and late-stage oncology clinical trials.
- Oversee biomarker assay development, qualification, and sample analysis in collaboration with internal teams and external CROs.
- Analyze and interpret biomarker data in the context of clinical outcomes and present results to cross-functional teams.
- Contribute to clinical protocols, study reports, and regulatory documents (e.g., INDs, IBs, CSRs).
- Translate preclinical findings into clinically actionable biomarker hypotheses.
- Stay current with emerging biomarker technologies and trends in precision oncology.
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
Education Level
Ph.D. or professional degree
