Senior Scientist I, Cancer Immunology
About The Position
Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: As a key player in our Cancer Immunology team, you will use your immuno-oncology expertise to help advance Revolution Medicines’ assets in preclinical and clinical development.
Requirements
- Ph.D. in immunology, cancer biology, or a related discipline, with deep expertise in tumor immunology, immuno-oncology biomarkers, and/or immunotherapy.
- Proven track record of research excellence, evidenced by high-impact publications.
- Expertise in in vivo model design to evaluate the efficacy and mechanisms of action of therapeutic agents and enable biomarker discovery, both internally and via contract research organizations.
- Strong technical expertise in immunology techniques including multi-parameter flow cytometric analyses, primary human cellular/tissue-based functional assays, cell biology and molecular biology to guide/inform mechanism of action and biomarker discovery.
- Strong problem-solving skills and ability to independently oversee scientific projects, rigorously analyze and interpret scientific data while maintaining attention to detail.
- Excellent written and verbal communication skills.
- Thrives in a fast-paced, collaborative, interdisciplinary team setting.
- 4+ years of relevant biotech or pharmaceutical industry experience in oncology drug discovery and development.
Nice To Haves
- Hands-on experience with humanized mouse models is desirable.
- Familiarity with multiomics analyses and integrating computational insights into experimental designs.
Responsibilities
- Design, develop, validate and execute in vitro, in vivo, and ex vivo studies to address key translational questions and support immuno-oncology biomarker plans.
- Identify, evaluate and implement emerging technologies to enhance translational biomarker discovery and mechanistic understanding.
- Drive reverse translation efforts by formulating and testing hypotheses derived from clinical finding as appropriate to inform clinical development plans.
- Stay abreast of advances in tumor immunology and immunotherapy, identifying novel combination strategies and contributing to preclinical evaluation.
- Analyze, interpret, and communicate complex data effectively across internal cross-functional teams and at external scientific meetings.
- Represent Revolution Medicines at scientific conferences and other external engagements.
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
Education Level
Ph.D. or professional degree
Number of Employees
501-1,000 employees
