Senior Scientist, Downstream Process Development (Contract)

Adverum Biotechnologies • Redwood City, CA

1d • $60 - $70

About The Position

Adverum, a wholly owned subsidiary of Eli Lilly and Company, is looking for a Senior Scientist to join our Process Development team in Redwood City. This individual will be a key member of the team, focusing on downstream activities. This is a 12-month contract with an opportunity for an extension.

Requirements

• Bachelor’s or advanced degree in chemical/biochemical engineering or related fields.
• 6-8 years of downstream purification experience in pharmaceutical or gene therapy manufacturing, including GMP-regulated operations.
• Hands on experience with buffer preparations, TFF (Hollow Fiber/Cassettes), UF/DF and Column Chromatography Purification.
• Experience working with AKTA Avant is required.
• Able to work in a fast-paced environment as a team player with effective communication skills.
• Excellent computer skills; especially proficient in Excel and Word.
• Strong desire to learn new technologies, skill sets, and science behind AAV processing.
• Strong teamwork and communication skills.

Nice To Haves

• Experience with statistical analysis software (e.g., JMP) and data visualization tools is a plus.
• Familiarity with regulatory guidelines and requirements for biologics manufacturing is a plus.

Responsibilities

• Perform pilot scale downstream purification process and manufacturing (post cell lysate to final formulation) by utilizing column chromatography, UFDF, and various filtration steps.
• Follow good documentation practices to maintain accurate records.
• Work closely with team members to perform buffer preparation.
• Set-up, operate and maintain required downstream laboratory equipment.
• Maintain reagent, sample, and consumables inventory.
• Assist with data entry and data analysis in Excel and/or other statistical programs.
• Ensure safe workplace in compliance with the company and EHS' rules and regulations.
• Work with Assay Development and Quality Control to coordinate testing.
• Work to optimize, and revise current process protocols, procedures, and batch records to make them more robust and streamlined.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Number of Employees: 11-50 employees