Scientist-Process Development (Contract)

Adverum Biotechnologies, Inc.Redwood City, CA
3d$45 - $55

About The Position

Adverum, a wholly owned subsidiary of Eli Lilly and Company, is looking for a Scientist to join the Process Development team at our Redwood City, CA office. The individual will be responsible for executing upstream pilot -scale rAAV production and expansion protocols and procedures. This is a 12-month contract with an opportunity for an extension.

Requirements

  • Bachelor’s or advanced degree in chemical/biochemical engineering or related fields.
  • 3-5 years of experience in pharmaceutical or gene therapy manufacturing, including GMP-regulated operations.
  • Hands-on experience in upstream cell culture process development and optimization, preferably in gene therapy.
  • Proficiency in operating and troubleshooting pilot-scale bioreactor systems, with a strong understanding of bioprocess engineering principles and practices.
  • Experience working with insect cell lines (e.g., Sf9) and viral vector production is highly desirable.
  • Excellent communication and teamwork skills, with the ability to collaborate effectively across functional teams.
  • Detail-oriented with strong problem-solving abilities and a proactive approach to challenges.
  • Some overtime required, as needed.

Nice To Haves

  • Experience with statistical analysis software (e.g., JMP) and data visualization tools is a plus.
  • Familiarity with regulatory guidelines and requirements for biologics manufacturing is a plus.

Responsibilities

  • Execute pilot-scale bioreactor runs according to established protocols and procedures.
  • Prepare and manage bioreactor systems, media, and solutions.
  • Perform cell culture inoculation, monitoring, and sampling during bioreactor runs.
  • Monitor and control critical process parameters to ensure optimal cell growth and product expression.
  • Troubleshoot process deviations and implement corrective actions as needed.
  • Collaborate with cross-functional teams to analyze and interpret process data.
  • Document experimental procedures, results, and observations in electronic laboratory notebooks and reports.
  • Work with cross-functional teams to coordinate sample testing.
  • Maintain a clean and organized laboratory environment and adhere to safety guidelines and regulations.
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