Senior Research Associate I, In Vivo

Crown BioscienceSan Diego, CA
5d$34 - $39

About The Position

We are seeking a highly skilled and detail-oriented Senior Research Associate to join our contract research team. The ideal candidate will have a strong background in experimental design, technical execution, and data integrity. This role requires exceptional organizational skills, the ability to work independently, and a commitment to delivering high-quality results under strict timelines. Summary The In-Vivo Senior Research Associate plays a critical role in the execution of in-vivo studies within a contract research environment. This position ensures the highest standards of animal welfare, precise technical execution, and accurate data collection to support client-sponsored projects. The role requires strong attention to detail, adherence to protocols, and the ability to perform advanced procedures with minimal supervision while fostering collaboration across teams.

Requirements

  • Bachelor's degree in animal science or related field
  • 5+ years of experience performing in-vivo procedures in a Vivarium environment is required
  • Comfortable working in a laboratory animal research environment
  • Demonstrated advanced technical expertise in essential in vivo murine oncology tumor models, including:
  • Animal handling
  • Tumor implantation and measurement
  • Gross necropsy
  • Drug preparation
  • Subcutaneous inoculations
  • Drug administration via multiple routes
  • Organ and tumor harvesting
  • Minor survival surgery
  • In-life and terminal blood collection

Nice To Haves

  • AALAS certification at LAT level or higher is preferred

Responsibilities

  • Work closely with Study Directors, Coordinators, and In-Vivo Managers to ensure studies follow protocols, SOPs, and company policies.
  • Track time spent on projects and maintain accurate project logs.
  • Prepare animals for procedures (e.g., shaving, ear tagging) and perform humane euthanasia in mice.
  • Ensure animal welfare and report abnormalities promptly.
  • Administer therapeutic agents via multiple routes (IP, PO, SC, IM, ID, IN, IV).
  • Perform subcutaneous inoculations, surgical implantations, and advanced in-vivo procedures with minimal supervision.
  • Demonstrate willingness to learn new techniques and procedures as necessary for sponsored projects, including complex techniques such as orthotopic implantations and model validation.
  • Collect body weight data, tumor volume measurements, and clinical observations.
  • Provide feedback to team members on project progress.
  • Collect tissue and blood samples; process and ship to sponsors or internal teams.
  • Track samples and facilitate timely shipment to sponsor companies.
  • Maintain clean workspaces, stock supplies, and assist with sample shipping.
  • Serve as team leader and/or mentor for other team members as needed.
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