Senior Research Associate, Antibody Engineering

Institute for Protein Innovation•Boston, MA

6d•$85,000 - $95,000

About The Position

This is a senior level science research position for an enthusiastic individual interested in high-throughput antibody discovery, production and characterization and concepts of bioengineering, biochemistry and robotic automation. Major responsibilities include but not limited to conducting and assisting in advancing the antibody discovery pipeline at IPI with day-to-day activities such as antibody expression and purification, QC and optimization, data analysis, reporting results, coordination with various IPI teams as well as external stake holders, and management of the pipeline in a Good Laboratory Practice environment. The candidate must be adaptable and willing to learn new techniques to help with daily IPI laboratory operations. The candidate must be engaged, well organized and detail oriented. This is an exciting opportunity to continue to learn industry leading antibody discovery platform technologies in a semi-academic environment. IPI provides a fast paced, highly knowledgeable and collaborative research environment.

Requirements

B.S. (with 4 years+) or MS (with 3 years+) in biological or life sciences field required
Experience with protein biochemistry and molecular biology
Experience with mammalian cell culture such as HEK293 cells, CHO cells
Familiar with running SDS-PAGE gel and Western Blot.
Experience with ELISA, PSR, DSF, SEC experiments.
Exceptional organizational and time-management skills and highly attentive to details
Strong verbal and written communications skills required
Excellent interpersonal skills and the ability to collaborate within a team-based environment is required
Enthusiastic team member with strong commitment to IPI’s mission and a desire to conduct impactful science

Nice To Haves

Basic understanding of fundamental programming (Python) helpful, but not required

Responsibilities

Antibody expression and purification in high-through form mammalian cell culture.
Operating laboratory automation equipment including Biomek.
Perform quality control analyses including Size Exclusion Chromatography (SEC), Plolyreactivity ELISAs, differential scanning florescence (DSF).
Mammalian cell culture maintenance.
Molecular biology skills such as DNA prep.
Provide support for ongoing projects within the team.
Assist in conducting experiments and working on research problems.
Coordinate time management, scheduling, product delivery and data sharing across Antibody Platform teams.
Maintain detailed records of experimental protocols and data in an electronic laboratory notebook in accordance with the Institute’s policy.
Present data clearly in a weekly group meeting.
Troubleshoot routine technical problems.