Senior Research Associate, Analytical Development

Lyell Immunopharma • Seattle, WA

1d • $95,000 - $118,000

About The Position

Using living cells to treat – and sometimes even cure – cancer is one of the most dramatic advances in modern medicine. Patients with hematologic malignancies have been successfully treated with cell therapies. However, these profound results have not yet been achieved in patients with solid tumors, representing approximately 90% of all cancers. And for patients with hematologic malignancies, there is a need for next-generation cell therapies that can deliver increased response rates and longer duration of response. We are a clinical-stage company advancing a pipeline of next-generation CAR T-cell therapies for patients with solid tumors or hematologic malignancies. Lyell’s product candidates are enhanced with novel technology designed to generate T cells that resist exhaustion and have qualities of durable stemness in order to drive durable tumor cytotoxicity and achieve consistent and long-lasting clinical response. We were founded by cell therapy pioneers whose decades of research elevated the broader understanding of T-cell biology and its interaction with cancer. In our quest to advance next-generation CAR T-cell therapies, we have built a fully integrated company capable of discovering new technologies, translating science into therapies, manufacturing cell therapy products, and clinically evaluating them in patients. Our culture is based on Science, Respect, Collaboration, and Courage and reflects who we are, the environment we create, and our mission's urgency.
The incumbent works collaboratively within their project team on the design and execution of a broad number of assays required for the project. With some supervision, works on com ex issues where analysis of situations or data requires an in-depth evaluation of variable factors. Exercises independent judgment in selecting methods, techniques and evaluation criteria for obtaining results. Begins to take on a central role in developing timelines for specific objectives within their projects. Responsible for keeping abreast of current publications relative to methods, techniques, and developments within the area of research, and will report on how new external learnings can be integrated into current projects. Networks with colleagues outside their own area of expertise. Responsible for carrying out a variety of experiments within the area of focus.

Requirements

• BSc in biotechnology, molecular biology, microbiology, immunology, oncology or related field with a minimum of 7 years' experience within the area of focus; or
• MSc in biotechnology, molecular biology, microbiology, immunology, oncology or related field with a minimum of 5 years' experience within the area of focus
• Understands the theoretical basis and experimental objectives and how they fit into the overall project goals
• Knowledgeable and proficient in a range of technical skills within their area of research

Nice To Haves

• Experience with molecular biology protocols (i.e. PCR, Western, RT-PCR, basic cloning); more complex experience a plus
• Experience using and analyzing common immunology and oncology related to the specific project; cell therapy experience ideal, more complex experience a plus
• Proficient in sterile tissue culture technique and experience working with human cells
• Experience with flow cytometry assays and analysis; more complex analysis and cell sorting experience a plus
• Experience in data production and reporting for IND-enabling studies
• Additional specific experience related to the area of focus may be required

Responsibilities

• Can design, execute and analyze experiments independently
• Generation, maintenance and review of electronic lab notebook reports
• Collaborate internally with Scientists to interrogate our novel therapies in our assays and models
• Interprets, troubleshoots and discusses data with Scientists and Research Associates at meetings or through reports
• Responsible for the completion of research, experiments and assignments that have an impact on functional goals

Benefits

• Lyell offers its employees a range of compensation and benefits.
• The salary range for this position is $95,000 to $118,000, annually, with the opportunity to earn an annual bonus.
• Employees are also eligible to participate in Lyell’s Equity Incentive Plan.
• Our Employee Benefits program is extensive and includes subsidized medical, dental and vision plans from your first day of employment, FSA, Company provided Life and AD&D Insurance as well as STD and LTD Insurance, ESPP, a 401(k) Plan with Company match, mass transit commuter benefits, cell phone reimbursement and a range of supplemental benefits that you may choose to elect.
• Our paid time-off benefits currently include Flex Time off, sick leave, 8 observed holidays as well as a floating holiday.
• We also have a winter office shutdown.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level