Senior/ Research Associate 2

Natera • San Carlos, CA

34d

About The Position

Natera is seeking a Senior/Research Associate 2 to support and coordinate workflow activities involved in the execution of molecular and genetic-based assays within the Molecular Biology Development team. The ideal candidate is a meticulous and motivated scientist with hands-on experience in assay development, capable of thriving in a dynamic, fast-paced environment to ensure the highest-quality clinical assays are developed and launched for patient care. This position plays a key role in the research, development, and optimization of molecular workflows that contribute to Natera’s cutting-edge products, including Signatera, our personalized molecular residual disease test, as well as new and emerging technologies in the in the cancer monitoring and detection space. The Senior Research Associate will work closely with scientists and engineers to execute experiments, perform analyses, and maintain efficient sample and data flow throughout development activities.

Requirements

• BS/BA in a biological science or equivalent
• Minimum of 4 years Molecular Biology laboratory experience required
• Minimum of 2 - 3 years of industry experience in an assay development department
• Hands-on experience with nucleic acid techniques, including DNA manipulation, PCR, qPCR, DNA quantification, and analysis using LabChip and BioAnalyzer systems
• Strong background in Next Generation Sequencing (NGS) techniques, protocols, and data analysis workflows
• Whole Blood processing (Isolation and extraction experience)
• Proficient in target enrichment, circulating cell-free DNA/RNA (cfDNA/cfRNA) processing, and library preparation for sequencing applications
• Automation skill set is a must, including experience with developing or executing assays on automated liquid handling platforms
• Experience with reagent quality control (QC) and troubleshooting assay performance
• Practical knowledge of LIMS/database query tools
• Proficient in data analysis using Excel and related software
• Strong analytical, organizational, and problem-solving abilities, with exceptional attention to detail
• Must have proven interpersonal, communication, computer, and technical skills
• Self-motivated, adaptable, and results-driven professional with a demonstrated track record of success in both independent and collaborative projects

Responsibilities

• Independently execute in-lab efforts both manually and using automated liquid handlers to develop non-invasive nucleic acid based diagnostic tests
• Experience with automation systems, particularly liquid handling platforms, is required for this role
• Assist in the design, execution, and troubleshooting of laboratory workflows in collaboration with scientists, engineers, and cross-functional teams
• Perform basic data analysis using tools such as Excel, JMP, or similar software
• Contribute to the preparation of reports and other deliverables
• Develop and maintain standard operating procedures (SOPs); provide training on established methods as needed
• Contribute to the optimization of new methods and technologies supporting next-generation oncology monitoring assays
• Coordinate with internal teams (e.g., Laboratory Operations, Scientific Operations, CLIA) to plan and improve logistical workflow processes
• Maintain compliance with Natera’s training, security, and privacy standards, including HIPAA/PHI and general policy requirements
• Adhere to environmental, health and safety (EHS) guidelines and good laboratory practices (GLP)
• Demonstrate flexibility in managing multiple priorities and perform additional duties as assigned

Benefits

• Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents.
• Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits.
• Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more.
• We also offer a generous employee referral program!

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Number of Employees: 1,001-5,000 employees