Senior Principal Scientist (R3-R4)

Lilly • Indianapolis, IN

2d

About The Position

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.
Eli Lilly and Company seeks a Senior Principal Scientist (R3-R4) to execute experiments on the cutting edge of pharmaceutical sciences. Support research programs for identified targets. Oversee aspects of portfolio programs independently by demonstrating laboratory expertise with biologic assays aimed at drug development (mAb, ADC, and CD3 platforms). Perform assay development for specialized assays related to portfolio programs. Perform functional mAb screening and profiling. Conduct evaluation of both in vitro and ex vivo assays. #LI-DNI

Requirements

• Position requires a Master’s degree in Biomedical Engineering, Bioengineering, or a related field, and 2 years of experience with drug development with mAb, ADC, and CD3 platforms.
• Experience must include a minimum of: 1 year of experience with phenotypic screens using human myeloid cells to identify novel immuno-oncology targets; 1 year of experience designing and implementing cellular assays to generate subsets of myeloid cells; 1 year of experience using multi-color flow cytometry, NanoString nCounter, and RASL sequencing to characterize myeloid culture systems; and 1 year of experience developing and optimizing flow cytometry, ELISA, and 32-plex Luminex based functional assays to validate the response of protein-based cancer vaccines in murine and cynomolgus models.
• Part-time telecommuting permitted.

Responsibilities

• Execute experiments on the cutting edge of pharmaceutical sciences.
• Support research programs for identified targets.
• Oversee aspects of portfolio programs independently by demonstrating laboratory expertise with biologic assays aimed at drug development (mAb, ADC, and CD3 platforms).
• Perform assay development for specialized assays related to portfolio programs.
• Perform functional mAb screening and profiling.
• Conduct evaluation of both in vitro and ex vivo assays.

Benefits

• Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance).
• Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).
• Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Number of Employees: 5,001-10,000 employees