Senior Principal Scientist, Psychiatry

Cogstate

9h•$165,000 - $180,000•Remote

About The Position

At Cogstate, we’re advancing the science of brain health - making it faster, easier, and more accurate to assess cognition across clinical trials, healthcare settings, and everyday life. Our digital cognitive assessments are trusted by researchers, clinicians, and pharmaceutical partners around the world, helping to drive breakthroughs in neuroscience and improve outcomes for people living with neurological conditions. Founded on decades of cognitive science and backed by rigorous validation, Cogstate’s assessments are used in more than 150 countries and over 2,000 clinical trials. Our global team of experts - spanning psychology, data science, operations, and technology - works together to solve complex challenges in brain health assessment, always with a patient-first mindset. Whether we’re supporting a multinational Alzheimer’s trial or developing tools to bring cognitive testing into routine care, our work is meaningful, collaborative, and constantly evolving. At Cogstate, we’re not just imagining the future of brain health - we’re building it. That’s why we’re seeking a Senior Principal Scientist, Psychiatry accountable for planning and overseeing the scientific strategy and delivery of psychiatry-focused clinical trial services across a portfolio of studies. This role is responsible for ensuring the scientific integrity, quality, and consistency of endpoint data collection, including rater training, scale administration, and central monitoring methodologies. The role provides scientific leadership across a portfolio of studies, supporting study design implementation and the development of services for psychiatric indications (e.g., MDD, schizophrenia, bipolar disorder). Responsibilities include oversight of rater training programs, central monitoring frameworks, and data quality strategies to support reliable and valid clinical trial outcomes.

Requirements

Tertiary qualifications or post graduate degree in the area of psychology, psychiatry, neuroscience, or related field
Evidence of scientific track record in publications, conference presentations, patents or grants, with maintenance of on-going professional development.
Experience in interacting with clinical scientists, neuropsychologists and medical professionals at a high level.
Experience managing scientific projects and directing staff.
At least 6 years of neuropsychological practical experience.
An understanding of the science of measuring cognition and behavior, including an understanding of computer-based tools and traditional neuropsychological assessment tools available to measure change in cognition in a clinical setting
Expertise in psychiatric rating scales (e.g., MADRS, PANSS, HAM-D, YMRS) and structured interview methodologies (e.g., SIGMA).
Experience with rater training, central monitoring, or data quality oversight.
5+ years of experience in clinical trials, with emphasis on CNS/psychiatry preferred.
Ability to organize and lead the organization of complex tasks and processes
Capable of critical thinking, problem solving, with ability to generate and present ideas and solutions.
Ability to use own initiative and pay close attention to detail
Ability to get on with people and work well in a team
Confidence to present a tailored presentation to a potential customer
A positive and determined approach to researching and analyzing new business opportunities
Strong client management skills
Commercial awareness

Responsibilities

Oversee the scientific delivery of psychiatry clinical trial services across a portfolio of studies, including rater training and central monitoring.
Contribute to definition and implementation of study-specific delivery plans for endpoint quality, including integration of central monitoring and review workflows.
Provide direction to internal study teams on feasibility, scale selection, administration standards, and timing of deliverables.
Serve as the primary scientific point of contact for assigned studies, ensuring clarity and consistency in internal and sponsor communications.
Contribute to design and implementation of rater training programs (e.g., MADRS, HAM-D, HAM-A, YMRS), including certification, calibration, and remediation pathways.
Monitor central monitoring outputs, including identification of data quality signals, rater drift, and protocol deviations, and guide appropriate follow-up actions.
Support the resolution of scientific and data quality escalations arising from central monitoring and study review activities.
Develop central monitoring resources to systematize feedback.
Collaborate with Project Management to ensure efficient and profitable delivery of services, including resource allocation and workflow optimization.
Contribute to the development and standardization of SOPs, training materials, and operational guidelines for psychiatry trials.
Support staff development within scientific and rater training teams, including mentoring and performance feedback.
Contribute to the development and refinement of psychiatry-focused products and services, including rater training programs, central monitoring methodologies, and scale-specific guidance.
Support innovation in endpoint quality assurance and approaches for detecting data quality issues.
Contribute to the design and interpretation of metrics related to rater performance, endpoint reliability, and data quality.
Analyze patterns in clinical trial data to identify risks such as placebo response inflation, rater drift, and scoring inconsistencies.
Provide scientific consultation on study design, scale selection, administration strategy, and risk mitigation.
Support business development through scientific input in proposals
Drive scientific dissemination through publications, conference presentations, and internal knowledge-sharing initiatives.
Contribute to advancing best practices in psychiatric endpoint assessment and central monitoring.

Benefits

Remote Work Practices: Cogstate is a virtual first company. Cogstate employees can work from anywhere where Cogstate is registered to business within the United States, Australia, or the United Kingdom!
Generous Paid Time-off: Cogstate employees receive 20 days of vacation leave, 10 days of personal leave and 10 paid public holidays.
401(k) Matching: As you invest in yourself and your future, Cogstate invests in you too: we match up to3% of your yearly salary in Cogstate’s 401k program.
Competitive Salary: We offer competitive base salaries plus additional earning opportunities based on the position.
Health, Dental & Vision Coverage: We've invested in comprehensive health & dental insurance options with competitive company contributions to help when you need it most. We also offer free vision insurance for all full-time employees.
Short-Term & Long Term Disability Life Insurance: 100% employer sponsored
Pre-Tax Benefits: Healthcare and Dependent Care Flexible Spending Accounts
Learning & Development Opportunities: Cogstate offers a robust learning program from mentorships to assistance with programs to improve knowledge or obtain certifications in applicable areas of interest.

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