Senior Principal Scientist - Medicinal Chemistry

Amgen•South San Francisco, CA

30d•Onsite

About The Position

Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Senior Principal Scientist Medicinal Chemistry What you will do Let’s do this. Let’s change the world. Amgen is hiring in the department of Medicinal Chemistry at our Research and Development facility in South San Francisco CA (ASF) where we are building brand new state-of-the art chemistry labs. Responsibilities: This Senior Principal Scientist role will be part of an innovative Medicinal Chemistry group, with primary responsibilities being the design of novel compounds for potential clinical development, while also serving as a Project Team Representative (PTR). In addition, this Senior Principal Scientist role will help recruit top talent and lead several PhD level chemists in the design and synthesis of potential drug candidates. As a manager of others, this role will be responsible for providing motivating professional development guidance and/or coaching of colleagues within their group. As a PTR, this role will typically also manage an external synthetic chemistry team and work together with a diverse cross-functional team of research scientists to help determine team direction and advance programs in Amgen’s small molecule portfolio. Additional responsibilities include but are not limited to regularly communicate progress and strategy in various forums. Expectations for this role are to be full time onsite at our Research and Development facility in South San Francisco CA (ASF). What we expect of you We are all different, yet we all use our unique contributions to serve patients. The qualified professional we seek is a Senior Principal Scientist with these qualifications.

Requirements

Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable] and 2 years of medicinal chemistry experience
Master’s degree and 5 years of medicinal chemistry experience
Bachelor’s degree and 7 years of medicinal chemistry experience

Nice To Haves

Doctorate degree in chemistry specializing in organic chemistry and 6+ years of experience in synthetic organic and medicinal chemistry
Experience participating on or leading medicinal chemistry teams to deliver candidates for clinical development
Track record of successful drug discovery accomplishments (e.g. patent inventorship, conference presentations, and peer-reviewed publications)
Proven understanding of relevant drug discovery disciplines (e.g. chemistry, biology, safety, PKDM, etc.)
Expert in modern medicinal and synthetic chemistry approaches
Demonstrated experience managing several direct reports
Excellent collaboration and communication skills (both written and oral)

Responsibilities

design of novel compounds for potential clinical development
serving as a Project Team Representative (PTR)
help recruit top talent and lead several PhD level chemists in the design and synthesis of potential drug candidates
providing motivating professional development guidance and/or coaching of colleagues within their group
manage an external synthetic chemistry team and work together with a diverse cross-functional team of research scientists to help determine team direction and advance programs in Amgen’s small molecule portfolio
regularly communicate progress and strategy in various forums

Benefits

health and welfare plans for staff and eligible dependents
financial plans with opportunities to save towards retirement or other goals
work/life balance
career development opportunities
Retirement and Savings Plan with generous company contributions
group medical, dental and vision coverage
life and disability insurance
flexible spending accounts
discretionary annual bonus program
sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models, including remote and hybrid work arrangements, where possible