Senior/Principal Scientist – Analytical Development (Contract)

Candel Therapeutics • Needham, MA

2d • $170,000 - $184,000 • Onsite

About The Position

Candel Therapeutics is seeking a highly qualified and experienced Senior or Principal Scientist to support analytical development activities on a contractual basis. The incumbent will contribute to the execution and oversight of laboratory operations, with a focus on cell-based assays and molecular methodologies. This role requires a strong foundation in GxP and ICH guidelines and involves cross-functional collaboration to support non-clinical, quality assurance, regulatory, and manufacturing functions.

Requirements

• M.S. or Ph.D. in Analytical Biochemistry, Molecular Biology, or a related scientific discipline; equivalent industry experience may be considered.
• Demonstrated expertise in analytical development, with a focus on cell-based and molecular assay techniques.
• Proficiency in GxP-compliant laboratory practices and familiarity with ICH regulatory standards.
• Strong analytical, organizational, and scientific writing skills.
• Availability to work on-site with 40% of time dedicated to laboratory-based activities.

Responsibilities

• Supervise and coordinate daily laboratory operations related to analytical development.
• Author and critically review analytical protocols, standard operating procedures (SOPs), and technical reports.
• Conduct comprehensive data analysis and ensure the accuracy and integrity of analytical results.
• Lead investigations into out-of-specification (OOS) results and deviations, including root cause analysis and implementation of corrective actions.
• Provide training and technical guidance to team members on the implementation of new assay methodologies.
• Collaborate with cross-functional stakeholders to ensure alignment of analytical deliverables with broader program objectives.
• Ensure all laboratory activities are conducted in compliance with applicable GxP regulations and ICH guidelines.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Number of Employees: 11-50 employees