Senior Oligonucleotide Chemist

Eurofins USA BioPharma ServicesLancaster, PA
Onsite

About The Position

Eurofins Scientific is an international life sciences company that provides analytical testing services across multiple industries, aiming to make life and the environment safer, healthier, and more sustainable. With 58,000 staff across 900 laboratories in over 54 countries, Eurofins is a global leader in various testing services, including food, environment, pharmaceutical, and cosmetic product testing, and agroscience Contract Research Organization services. In 2024, Eurofins generated total revenues of EUR 6,515 billion. The Oligonucleotide Scientist is responsible for developing, optimizing, validating, and executing analytical methods to support oligonucleotide API, drug substance, and drug product testing. This role primarily focuses on HPLC/UHPLC and mass spectrometry (e.g., LC MS, LC MS/MS) for identity, purity/impurity profiling, quantitation, and stability-indicating assessments. The scientist will be responsible for authoring methods, protocols, and reports, ensuring data integrity and compliance within GxP environments, and providing technical leadership for routine testing and investigations, as well as mentoring junior staff. The position requires the application of GMP in all areas of responsibility.

Requirements

  • Applicants MUST have authorization to work in the U.S. indefinitely without restriction or sponsorship
  • BS or MS degree in analytical chemistry or other related degree concentration
  • BS and 4+ years of industry experience, MS and 2+ years of industry experience, or PhD and 1+ year of industry experience
  • Industry experience with oligonucleotides and drug product testing
  • 3-5 years of experience with LC chromatographic validation in a GMP environment
  • Authorization to work in the U.S. without immediate or future sponsorship

Nice To Haves

  • Excellent communication (oral and written) and attention to detail
  • Ability to work independently and as part of a team, self-motivation, adaptability, and a positive attitude
  • Ability to learn new techniques, perform multiple tasks simultaneously, keep accurate records, follow instructions, and comply with company policies

Responsibilities

  • Developing, optimizing, validating, and executing analytical methods to support oligonucleotide API, drug substance, and drug product testing
  • Focusing primarily on HPLC/UHPLC and mass spectrometry (e.g., LC MS, LC MS/MS) for identity, purity/impurity profiling, quantitation, and stability-indicating assessments
  • Authoring methods, protocols and reports
  • Ensuring data integrity and compliance within GxP environments
  • Providing technical leadership for routine testing and investigations
  • Mentoring of junior staff
  • Applying GMP in all areas of responsibility, as appropriate
  • Performing a large variety of analytical tasks for the validation of analytical methods used in the testing of drug products and raw materials by means of various procedures including HPLC, GC, UV/Vis, and dissolution
  • Reading, understanding, and interpreting diverse analytical procedures
  • Conducting analytical investigations
  • Troubleshooting instrumentation and communicating with vendors when required
  • Training and mentoring junior staff in laboratory procedures
  • Managing and discussing projects with clients

Benefits

  • Excellent full time benefits including comprehensive medical coverage, dental, and vision options
  • Life and disability insurance
  • 401(k) with company match
  • Paid vacation and holidays

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What This Job Offers

Job Type

Full-time

Career Level

Senior

Number of Employees

5,001-10,000 employees

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