Senior Manager, Operational Excellence and Project Management, Hypercell

Bristol Myers Squibb • Devens, MA

1d • Hybrid

About The Position

Working with Us Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us. Position Summary The Hypercell team is focused on transforming cell therapy operations by streamlining supporting processes through digital, automation, and AI-driven solutions. We are seeking an Operational Excellence and Project Management Lead to drive continuous improvement, standardization, and efficiency across the cell therapy network. This role will be instrumental in identifying and eliminating waste, improving process reliability, and enabling scalable operations through data-driven insights and cross-functional collaboration.

Requirements

• Bachelor’s or Master’s degree in Engineering, Life Sciences, Business, or related field.
• 5+ years of experience in operational excellence, manufacturing, or process improvement roles, preferably in cell therapy, biologics, or regulated biopharma environments.
• Strong knowledge of Lean, Six Sigma, and other continuous improvement frameworks; certification preferred.
• Experience with digital transformation, automation, and data analytics tools.
• Proven ability to lead cross-functional teams and drive measurable results.
• Excellent communication, facilitation, and stakeholder engagement skills.

Nice To Haves

• Familiarity with GMP manufacturing and regulatory requirements for advanced therapies.
• Experience supporting digital and AI initiatives in a manufacturing or technical operations context.
• Ability to translate complex operational challenges into actionable improvement plans.

Responsibilities

• Support the Hypercell team define transformative processes, applying Lean, Six Sigma, and other continuous improvement methodologies to existing business processes to drive innovation.
• Partner with process engineering, quality and operations teams to identify and develop projects with opportunities for simplification, automation, and standardization. This individual will support multiple projects from both an OpEx and project manager perspective.
• Develop and maintain performance metrics, dashboards, and reporting tools to monitor progress and drive accountability.
• Facilitate activities across Hypercell including, value stream mapping, lean processing, and Kaizen events to address operational pain points and unlock efficiencies.
• Facility project mapping, timelines and critical dependencies to ensure projects are delivered on time and in full.
• Support the deployment of AI-facing tools and digital solutions that enhance decision-making and reduce manual effort.
• Collaborate with site and global stakeholders to harmonize best practices and ensure alignment with broader Cell Therapy and Global Product Supply strategies.
• Champion a culture of continuous improvement, operational discipline, and innovation across the team.
• Author and contribute to documentation including SOPs, training materials, and change control packages.

Benefits

• Health Coverage: Medical, pharmacy, dental, and vision care.
• Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
• Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
• Work-life benefits include: Paid Time Off US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees) Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays Based on eligibility, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day. All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Number of Employees: 5,001-10,000 employees