Senior Manager, Commercial Data Management

Cogent Biosciences • Waltham, MA

36d

About The Position

Cogent Biosciences is a publicly traded biotechnology company dedicated to developing precision therapies for genetically defined diseases. By leveraging validated biology and a rational drug discovery approach, Cogent aims to create real solutions that address the underlying drivers of disease and offer meaningful hope to patient's. The company’s lead therapeutic candidate, Bezuclastinib, is a highly selective tyrosine kinase inhibitor designed to potently target KIT D816V and other mutations in KIT exon 17. These mutations are known drivers of systemic mastocytosis (SM) and advanced gastrointestinal stromal tumors (GIST) - both serious conditions driven by oncogenic KIT signaling. Bezuclastinib is currently being evaluated in multiple registration-directed trials across Non-Advanced SM (NonAdvSM), Advanced SM (AdvSM), and GIST. In July 2025, Cogent announced that its registration-direct SUMMIT trial in patients with NonAdvSM achieved statistical significance across all primary and key secondary endpoints, and the company is on track to file its first New Drug Application for this patient population by the end of 2025. The company also remains on track to announce top-line results for its APEX trial in patients with AdvSM in the second half of 2025 and for its PEAK trial in patients with GIST by the end of 2025. The company also has an ongoing Phase 1 study of its novel internally discovered FGFR2 inhibitor, and the Cogent Research Team is developing a portfolio of novel targeted therapies to help patients fighting other serious, genetically driven diseases targeting mutations in ErbB2, PI3Kα and KRAS. Through its commitment to precision medicine and targeted innovation, Cogent Biosciences is working to transform the treatment landscape for patients with serious and underserved diseases. By leveraging validated biology and a rational drug discovery approach, Cogent aims to create real solutions that address the underlying drivers of disease. Our culture of inquisitiveness fuels continuous learning and innovation; we challenge assumptions, ask bold questions, and embrace a mindset of discovery to uncover transformative insights. We are seeking a Senior Manager, Commercial Data Management to join our Commercial Operations and Analytics team. This role is critical to build and scale the data foundation that supports our commercial organization as we prepare to launch Bezuclastinib across 3 important indications, Cogent Biosciences’ key pipeline asset. This role will be pivotal in ensuring data integrity, accessibility, and actionable insights across the commercial ecosystem. The ideal candidate combines strategic vision with hands-on technical expertise in data management, reporting, dashboarding, and advanced analytics.

Requirements

• Bachelor’s degree in Data Science, Analytics, Information Systems, or related field; Master’s preferred.
• 5+ years of experience in Commercial Data Management, Analytics, or Sales Operations within pharmaceutical/biotech industry.
• Strong understanding of rare disease and oncology market dynamics preferred.
• Hands-on experience with SQL, data warehouse platforms (Snowflake, Databricks, Oracle), and BI tools (Tableau, Power BI).
• Familiarity with CRM systems (Salesforce, Veeva) and syndicated data sources (IQVIA, Symphony, MMIT).
• Proven ability to design scalable data solutions and deliver actionable insights in a regulated environment.
• Excellent communication and stakeholder management skills.

Nice To Haves

• Experience with advanced analytics techniques (predictive modeling, machine learning).
• Knowledge of specialty pharmacy and specialty distributor data flows.
• Ability to operate strategically while remaining hands-on in technical execution.

Responsibilities

• Design, implement, and maintain the commercial data architecture, including data warehouse development and optimization.
• Oversee master data sets (Customer, Product, Payer) ensuring accuracy, compliance, and governance.
• Manage data integration projects across CRM (Salesforce/Veeva), specialty pharmacy/distributor data, and third-party sources (IQVIA, Symphony, MMIT).
• Establish and enforce data governance standards, policies, and procedures.
• Develop and maintain dashboards and reports using BI tools (Tableau, Power BI) to track KPIs, sales performance, and launch metrics.
• Enable advanced analytics capabilities, including predictive modeling and segmentation, to inform commercial strategy and resource allocation.
• Partner with Sales Operations and Marketing to deliver actionable insights for targeting, alignment, and promotional effectiveness.
• Provide analytical support for product launch readiness, including market analysis, performance tracking, and competitive intelligence.
• Collaborate with cross-functional teams (Marketing, Finance, IT) to ensure data-driven decision-making during launch execution.
• Support incentive compensation processes, including coordinating with vendors on IC plan modeling, scorecard creation, data validation, and timely distribution of monthly/quarterly results.
• Manage territory alignments and roster changes, partnering with Sales Leadership and MDM/CRM teams to implement updates, maintain accuracy, and ensure clean downstream reporting.
• Drive key operational activities across the commercial organization, including data pulls, roster management, field communications, system updates, and cross-functional workflow support.
• Query and extract data from the data warehouse using SQL and other tools.
• Ensure data quality and timeliness for all reporting and analytics deliverables.
• Manage relationships with data vendors and oversee data acquisition processes.

Benefits

• To attract the very best talent, we offer a generous benefits package that includes competitive pay, performance-based bonus, stock options, insurance coverage (health, dental, life, and disability), competitive time-off, a 401(k) plan, and commuter/parking benefits.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Number of Employees: 101-250 employees