Senior Director, Strategic Portfolio Management Team Lead

Pfizer • New York City, NY

6d • Hybrid

About The Position

Are you energized by the chance to bring clarity and simplicity to complex challenges? As Senior Director, Strategic Portfolio Team Lead, you’ll transform Pfizer’s digital portfolio management from a patchwork of processes into a unified, streamlined engine for innovation. You’ll architect the standards, tools, and practices that empower portfolio leaders across every Center of Excellence and Creation Center to deliver on our boldest ambitions. You will serve as the enterprise architect and challenger for Pfizer’s digital investment agenda - ensuring every initiative is rigorously aligned to our digital strategy and future vision. You will partner with the Portfolio Leads to proactively inspect, challenge, and recommend bold moves to optimize resource allocation, accelerate value creation, and drive operational discipline. You will influence and enable the Digital & Technology Leadership Team to act with discipline and foresight—making recommendations that help fund the few, finish the vital, and re-balance as priorities shift.

Requirements

• A bachelor’s degree (digital technology preferred)
• 12+ years in portfolio management, strategy, or program leadership roles.
• Proven experience developing and implementing enterprise-wide standards or tools.
• Demonstrated ability to lead cross-functional teams and influence at the executive level.
• Experience with digital transformation and AI-enabled portfolio practices.
• Recognized thought leader in digital transformation and portfolio management.
• Experience leading in large, matrixed organizations.
• Strong analytical skills and proficiency with portfolio management tools.
• Exceptional communication and stakeholder engagement capabilities.

Nice To Haves

• MBA or relevant advanced degree
• Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

Responsibilities

• Enterprise Portfolio Strategy & Governance Set and govern the standards, methodologies, and tools for portfolio management across the enterprise, ensuring consistency, transparency, and strategic alignment.
• Lead cross-functional prioritization and value realization efforts, partnering with Digital & Technology LT and portfolio leads to optimize resource allocation and maximize business impact.
• Continuously assess the portfolio through rigorous reviews, surfacing start/stop/scale recommendations that keep investments aligned to Pfizer’s digital strategy.
• Innovation & Continuous Improvement Champion the integration of AI, advanced analytics, and best-in-class practices to modernize portfolio management and accelerate decision-making.
• Act as a change agent, driving continuous improvement and fostering a culture of innovation and accountability.
• Identify low-value work, bottlenecks, and duplication across portfolio processes; recommend simplification, standardization, and automation in partnership with Digital Process Reinvention Lead.
• Strategic Collaboration & Influence Collaborate with the Portfolio Value Storyteller and Reinvention team to ensure a unified, compelling narrative for digital investments and to reimagine portfolio processes.
• Influence senior management decisions, providing strategic recommendations that shape the direction of Pfizer’s digital transformation.
• Make actionable recommendations to Digital & Technology leaders on portfolio optimization.
• Center of Excellence Leadership Operate as the strategic leader of a Center of Excellence for portfolio management, ensuring that standards, insights, and innovations are shared and adopted across all business units.
• Leadership & Enablement Build, mentor, and empower a high-performing team (2–4 direct reports), cultivating a culture of innovation, accountability, and continuous learning.
• Mobilize matrixed resources and partnerships to deliver breakthrough results.
• Provide transparent insights, dashboards, and decision intelligence that enable senior leaders to act proactively and decisively.

Benefits

• participation in Pfizer’s Global Performance Plan with a bonus target of 22.5% of the base salary and eligibility to participate in our share based long term incentive program
• 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution
• paid vacation, holiday and personal days
• paid caregiver/parental and medical leave
• health benefits to include medical, prescription drug, dental and vision coverage

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Number of Employees: 5,001-10,000 employees