Senior Director, Medical Affairs (West)

Vaxcyte•San Carlos, CA

2h•$266,000 - $310,000•Remote

About The Position

Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance. Summary: The Senior Director, Medical Affairs is a senior leadership role responsible for shaping and executing the medical strategy for the company’s vaccine portfolio. This position combines traditional headquarters medical affairs responsibilities with direct oversight of a Medical Science Liaison (MSL) team and engagement with national vaccine recommending bodies and professional organizations. The role ensures scientific excellence, compliance, and alignment with Vaxcyte and public health priorities.

Requirements

Advanced degree (PharmD, PhD, MD, or equivalent) in life sciences, immunology, infectious diseases, or public health. A minimum of 12 years progressive experience in medical affairs, including leadership roles.
Proven track record in vaccines or infectious disease therapeutic areas.
Experience managing MSL teams and integrating field insights into HQ strategy.
Strong understanding of immunization policy, public health systems, and regulatory frameworks.
Exceptional communication, presentation, and interpersonal skills.
Ability to travel up to 70% of the time.
Other combinations of education and/or experience may be considered.

Responsibilities

Contribution to development and implementation of medical affairs strategy for vaccines across the product lifecycle.
Provide scientific and clinical expertise to support regulatory submissions, labeling, and safety monitoring.
Collaborate with clinical development, regulatory, and commercial teams to ensure consistent scientific messaging.
Offer strategic input and thought leadership in publication planning, medical education, and evidence generation initiatives.
Monitor emerging data, guidelines, and competitive intelligence to inform strategy.
Manage and mentor a team of MSLs, ensuring effective scientific exchange and stakeholder engagement.
Align field insights with HQ strategy to drive evidence-based decision-making.
Establish performance metrics and professional development pathways for MSLs.
Foster collaboration between HQ and field medical teams to ensure seamless execution.
Build and maintain relationships with key organizations making vaccine recommendations
Represent the company in scientific and policy discussions related to immunization guidelines and vaccine adoption.
Provide medical leadership at advisory boards, scientific congresses, and public health forums.
Influence vaccine policy and recommendations through evidence-based advocacy.