Senior Director, Device Portfolio Insights

Eli Lilly and Company•Indianapolis, IN

About The Position

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world. Position Summary: The Senior Director of Device Portfolio Insights serves as enterprise owner of device portfolio strategy, investment prioritization, and long-range value creation. This role orchestrates cross-functional integration across R&D, Clinical, Therapeutic Areas, Commercial, Finance, and Digital to drive portfolio decisions that maximize strategic and financial return. This leader provides oversight of portfolio health, prioritization, and governance while ensuring integration between drug delivery devices and Lilly's clinical pipeline. Serving as the central hub for portfolio intelligence, this role drives resource allocation, investment optimization, and AI-enabled decision support. The position requires sophisticated analytical capabilities and the ability to synthesize complex information into actionable insights that guide executive decision-making.

Requirements

Bachelor's degree in relevant discipline (Business, Engineering, Life Sciences, Data Science, Operations Research) with a minimum of 15 years of experience in pharmaceutical and medical device R&D, portfolio management, strategy, or related functions
Proven track record managing complex, multi-million-dollar portfolios with cross-functional dependencies
Significant experience with drug delivery systems, medical devices, or combination products
Demonstrated experience in resource management and capacity planning for R&D organizations
Experience with pharmaceutical governance processes and investment decision-making
Strong background in financial analysis, business case development, and investment optimization

Nice To Haves

Advanced degree (MBA, MS, PhD) in relevant discipline (Business, Engineering, Life Sciences, Data Science, Operations Research) with a minimum of 10 years of progressive experience in pharmaceutical and medical device R&D, portfolio management, strategy, or related functions
Deep knowledge of portfolio management principles, frameworks, and best practices
Experience with portfolio optimization methodologies and decision analysis techniques
Proficiency with portfolio management tools and software (e.g., Planisware, Clarity, ServiceNow, Tableau)
Understanding of stage-gate processes and governance frameworks in pharmaceutical R&D
Knowledge of portfolio metrics, KPIs, and performance measurement systems
Experience with agile portfolio management and adaptive planning approaches

Responsibilities

Strategic Mandate and Enterprise Ownership Develop and maintain a comprehensive, integrated view of the device development portfolio spanning drug delivery pre-clinical & clinical research, device innovation, development, and commercialization projects, programs, and initiatives under device development
Ensure seamless integration between drug delivery device development and Lilly's clinical molecule pipeline across all therapeutic areas
Support annual portfolio strategic planning processes in collaboration with device development leadership
Use market analysis, competitive intelligence, and technology assessments to inform portfolio strategy
Identify whitespace opportunities and recommend new investment areas.
Support build vs. buy vs. partner analyses for delivery system capabilities
Cross‑Functional Orchestration Leverage deep portfolio knowledge and financial expertise to optimize investment strategies at both project and portfolio levels
Partner with Finance and PPM/CMC PM teams to develop accurate cost models, forecasts, and business cases for drug delivery system initiatives
Track and report on portfolio expenditures, variance analysis, productivity, and return on investment metrics
Support business case development for new initiatives and portfolio prioritization decisions
Develop and update device development archetypes and support disease state benchmarking activities
Decision-Focused Portfolio Intelligence Develop, maintain, and continuously enhance the device development portfolio dashboard to support data-driven decision-making
Establish key performance indicators (KPIs) and metrics that provide meaningful insights into portfolio health, progress, and value realization
Create visualizations and reporting tools that enable leadership to quickly assess portfolio status, risks, and opportunities
Implement predictive analytics and modeling capabilities to forecast portfolio outcomes
Artificial Intelligence and Decision Science Leadership Champion use of decision science, data science, and AI applications in device development business intelligence to improve portfolio operations
Deploy predictive analytics and decision augmentation tools to enhance portfolio forecasting, risk assessment, scenario planning, and opportunity identification
Identify resource constraints, bottlenecks, and capability gaps; recommend solutions
Monitor resource utilization metrics and drive continuous improvement in capacity management
Forward‑Looking Portfolio Deployment Ensure clear and consistent communication of portfolio status, insights, and recommendations to device development leadership and cross-functional stakeholders
Facilitate regular portfolio communication forums to share insights, trends, and priority shifts
Identify, assess, and communicate portfolio-level risks, dependencies, and integration challenges.
Develop risk mitigation strategies and contingency plans for high-impact portfolio risks
Ensure transparent escalation of critical issues requiring leadership attention or intervention
Build strong relationships with therapeutic area leaders, clinical development teams, and commercial stakeholders
Translate complex portfolio data into compelling narratives for executive audiences
Serve as Strategic Portfolio leader Prepare portfolio materials for governance reviews, decision forums, and executive leadership meetings
Ensure governance readiness by maintaining current, accurate data on milestones, deliverables, risks, and dependencies
Act as a trusted advisor to leadership on portfolio strategy and investment decisions

Benefits

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance).
In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).

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