Senior CTMS Delivery Product Manager (Salesforce)

Natera • Austin, TX

18d

About The Position

The Senior CTMS Delivery Product Manager is responsible for technical delivery, system design coherence, and architectural integrity of the Salesforce-based Clinical Trial Management System (CTMS), including Cloudbyz components. This role sits within the technology organization and serves as the technical design authority for CTMS delivery , ensuring that ClinOps-owned business decisions and outcomes are implemented using a holistic, end-to-end system architecture that supports scalability, compliance, and long-term maintainability. The role focuses on how CTMS changes are designed and delivered technically, while system roadmap and final business decisions remain with Clinical Operations , consistent with the CTMS governance model .

Requirements

• 10+ years of experience in technical product management, system architecture, or enterprise application delivery
• Hands-on experience designing and delivering Salesforce-based platforms
• Strong experience with CTMS platforms
• Proven ability to act as technical design authority while operating within a business-owned governance model
• Experience in GxP-regulated environments with validated systems

Nice To Haves

• Experience combining delivery ownership and system architecture responsibilities
• Familiarity with EDC, eTMF, IRT, safety, and financial systems
• Salesforce certifications (Admin, Platform App Builder, Integration Architecture Designer)
• PMI Certification

Responsibilities

• Act as the CTMS Technical System Architect for Salesforce and Cloudbyz implementations
• Maintain a holistic architectural view of the CTMS platform across: Study, site, subject, and financial modules
• Integrations with EDC, eTMF, IRT, ERP, and analytics systems
• Evaluate proposed changes for cross-module, cross-study, and cross-system impacts
• Define and enforce technical design standards , data models, and integration patterns
• Prevent fragmented, study-specific configurations that introduce technical debt
• Serve as the IT delivery owner for CTMS enhancements and platform changes
• Execute delivery against a ClinOps-defined and approved CTMS roadmap
• Manage Cloudbyz as an IT vendor , ensuring execution aligns with internal architectural standards
• Lead Agile delivery activities including backlog refinement, sprint planning, and release execution
• Balance configuration vs. customization decisions to support scalability and maintainability
• Partner with Clinical Systems and business stakeholders to: Review approved change requests from a system-design and delivery feasibility perspective
• Translate requirements into technically sound user stories and acceptance criteria
• Surface architectural risks and recommend alternative technical approaches when business requests may compromise system integrity or scalability
• Provide technical product leadership across: Salesforce configuration, customization, automation, and reporting
• Cloudbyz CTMS modules and extensions
• Coordinate and oversee integrations to ensure data consistency and architectural alignment
• Collaborate with developers, architects, and vendors to ensure adherence to CTMS delivery standards
• Design and deliver CTMS changes that support: GxP principles
• 21 CFR Part 11 requirements
• Validation and audit readiness
• Partner with Quality and Clinical Systems to support CSV activities , recognizing that validation accountability resides with Quality
• Communicate delivery status, architectural decisions, and technical risks to: Clinical Systems leadership
• IT leadership
• Serve as the escalation point for technical design and delivery conflicts
• Proactively identify systemic design issues and delivery risks before they impact production or compliance

Benefits

• Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents.
• Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits.
• Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more.
• We also offer a generous employee referral program!

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: No Education Listed