Senior Associate Scientist -Cell Line Development

SanofiFramingham, MA
1dHybrid

About The Position

We seek a highly motivated candidate to join Cell Line Development (CLD), assisting and responsible for generating mammalian cell lines for Sanofi’s R&D biologics pipeline and implementing new technologies and processes for continuous platform improvement. CLD, located in Framingham MA, is a global function, supporting research and early development projects at three Sanofi R&D Hubs (North America, France, Germany), and team members routinely work with colleagues at different sites. The person in this role will work in a high-performing, fast-paced collaborative environment, ensure project goals and timelines are met, and help drive optimization for cell line production of biologics including antibodies and diverse, novel formats. Work will directly support development projects within Sanofi’s pipeline. The position also provides the opportunity to work on global teams, contribute to operational excellence and other transversal initiatives, and have a direct impact on shaping our future cell line expression platforms. Join the engine of Sanofi’s mission — where deep immunoscience meets bold, AI-powered research. In R&D, you’ll drive breakthroughs that could turn the impossible into possible for millions. About Sanofi: We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.

Requirements

  • Master's Degree in Biology, Cell Biology, Molecular Biology, Bioengineering, or related discipline, or Bachelor’s degree in relevant discipline with >2yr of relevant experience.
  • Hands-on experience in mammalian cell line development in a pharmaceutical or biotechnology setting.
  • Strong technical background and attention to detail.
  • Self-motivated with excellent communication, organization and time-management skills.
  • Demonstrated ability to work independently and in a highly collaborative environment and adhere to timelines.

Nice To Haves

  • Suspension mammalian cell culture experience (CHO cell culture) in a pharmaceutical or biotechnology setting.
  • Experience with advanced molecular biology skills.
  • Experience with automation and/or high throughput technologies as applied to mammalian cell line generation and process optimization is highly preferred.
  • Experience and working knowledge in high-throughput screening tools (bioreactors, analytics) for cell line selection.
  • Excel in a past-faced highly cooperative team environment, ability to multitask, adaptability and positive attitude.

Responsibilities

  • Perform mammalian cell culture techniques: sterile technique, cell counting, passaging, cryopreservation, etc.
  • Perform basic molecular biology techniques: DNA plasmid preparation, PCR, restriction enzyme digestion, etc.
  • Perform cell culture techniques for both pool and clone generation of expressive populations and cell lines expressing biotherapeutics.
  • Work package also includes all other associated activities for selection of the final cell line. Some activities may also include banking, stability studies, copy number and transcript analysis.
  • Assist in several studies simultaneously to optimize cell line generation processes. Flexibility, adjusting to a fast-paced, goal-oriented environment and willingness to expand and broaden one’s skillset.
  • Prepare reports, presentations, and data sets to effectively communicate results, progress and plans, presentation at lab meetings.
  • Contribute to lab organization, reagent tracking and other assigned tasks as determined appropriate.
  • Compliance with all applicable regulations, ensure that work performed is conducted in a safe and compliant manner, maintenance of proper records in accordance with SOPs and policies.

Benefits

  • Bring the miracles of science to life alongside a supportive, future-focused team.
  • Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.
  • Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
  • Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.
  • Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real-world needs.
  • Help improve the lives of millions of people globally by making drug development quicker and more effective.
  • Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science.
© 2024 Teal Labs, Inc
Privacy PolicyTerms of Service