Scientist, Potency and Functional Characterization

Bristol Myers Squibb•Seattle, WA

About The Position

Working with Us Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us . Position Summary We are seeking a highly motivated professional to join the Cell Therapy Analytical Development team, specializing in cell line engineering and potency method development for viral vector applications. The ideal candidate will contribute to the optimization and qualification of cell-based viral vector transduction assays measured by flow cytometry and luminescent reporter genes. This position demands a strong foundation in cell culture, keen attention to detail, and enthusiasm for solving scientific challenges in a fast-paced, collaborative environment. Successful candidates will demonstrate competency in these areas and contribute to breakthrough developments in cell therapy.

Requirements

Ph.D. in Immunology, Cell Biology, Bioengineering, or a related field with 0–3 years of industry experience; or an MS/BS with 5+ years of relevant laboratory experience.
Proficiency in cell culture, viral vector transduction, cell line engineering, flow cytometry, and relevant analytical assays (e.g., ELISA).
Strong organizational, documentation, and communication skills.
Ability to thrive in a collaborative, fast-paced, and dynamic environment.

Nice To Haves

Experience with JMP and SoftmaxPro softwares is preferred.
Experience with vector construct design is highly desirable.
Background in DNA/RNA transfection, viral vector transduction, and potency release method development is preferred.

Responsibilities

Generate monoclonal cell lines and establish cell banks by transducing cells with viral vectors, expanding the cultures, isolating monoclonal populations through cell sorting, banking the validated cell lines, and performing functional qualification using lot-release potency and flow cytometry assays.
Design and execute laboratory experiments to optimize DNA/RNA transfection, viral transduction, flow cytometry and plate based potency reporter gene assay parameters and procedures to meet the pre-defined analytical target profile.
Contribute to method qualification and transfer activities based on ICH/USP guidelines.
Analyze complex data sets, perform data trending and visualization, and maintain detailed experimental records in ELN for reproducibility and quality assurance.
Document cell line generation processes and experimental findings, contributing to SOPs, technical reports, and regulatory filings to ensure compliance and support innovation.
Cultivate and maintain cell lines and primary cells essential for innovative assay development.
Manage lab operations by overseeing inventories, scheduling equipment maintenance, and implementing process improvements for efficiency and productivity.

Benefits

Medical, pharmacy, dental and vision care.
Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP).
Financial well-being resources and a 401(K).
Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support.
Work-life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Year’s holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility.
Parental, caregiver, bereavement, and military leave.
Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources.
Other perks like tuition reimbursement and a recognition program.

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