Scientist, Pharmacokinetics
About The Position
We are seeking a dynamic and collaborative Scientist to contribute to our Company's drug discovery and early clinical development efforts, with a focus on lab-based bioanalysis for small molecules and peptides. This position will be based in the Drug Metabolism and Pharmacokinetics (DMPK) Group within the Pharmacokinetics, Dynamics, Metabolism and Bioanalytics (PDMB) organization at our Company's Research Laboratories in West Point, PA. The successful candidate will be responsible for execution and troubleshooting of quantitative bioanalytical methods in support of in vitro studies, delivering high quality data and maintaining bioanalytical laboratory operations compliant with all applicable internal and regulatory guidelines and standard operating procedures. The candidate should be motivated to work in a highly collaborative and fast-paced environment.
Requirements
- Good understanding of analytical chemistry, including liquid chromatography and mass spectrometry
- Quantitative analysis of small molecules and peptides using LC-MS and other analytical techniques
- Manual and automated sample preparation techniques including protein precipitation and solid phase extraction
- Strong interpersonal skills and the ability to work as part of a high-performing team
- Experience or interest in robotics, assay automation, and operation of liquid handlers in support of high throughput workflows
- Proficient in Microsoft Office
- Clear oral and written communication
- Accountability
- Analytical Chemistry
- Assay
- Bioanalysis
- Biochemistry
- Biopharmaceuticals
- Cell Culture Techniques
- Chemical Engineering
- Clinical Development
- Clinical Judgment
- Data Analysis
- Data Visualization
- Detail-Oriented
- Drug Metabolism
- Ethical Compliance
- GMP Documentation
- Good Laboratory Practices (GLPs)
- Immunoassays
- Laboratory Documentation
- Ligand Binding Assay
- Liquid Chromatography-Mass Spectrometry (LC-MS)
- Mass Spectrometry (MS)
- Parasitology
- Pharmacodynamics
Nice To Haves
- Basic understanding of statistical analysis.
- Ability to design, interpret and troubleshoot experiments aimed at addressing complex questions
- Familiarity with electronic laboratory notebooks and related record-keeping approaches
- Experience working within a research-driven pharmaceutical company
Responsibilities
- Execution and troubleshooting of quantitative bioanalytical methods in support of in vitro studies
- Delivering high quality data
- Maintaining bioanalytical laboratory operations compliant with all applicable internal and regulatory guidelines and standard operating procedures
Benefits
- The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.
- We offer a comprehensive package of benefits.
- Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days.
- More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.
Stand Out From the Crowd
Upload your resume and get instant feedback on how well it matches this job.
What This Job Offers
Job Type
Full-time
Career Level
Entry Level
