Scientist, Oncology Translational Research

Bristol Myers Squibb

1d • Onsite

About The Position

The Oncology Thematic Research Center at BMS is a key research and early development engine, responsible for the discovery and development of novel oncology therapeutics for patients. Centered at our state-of-the-art research sites in Cambridge and Seattle, scientists focus on novel targets and pathways for tumors that are refractory to current therapies. With a deep understanding of the causal human biology, we are able to leverage our multiple modality platforms to best match the modality to the mechanism and desired outcome. We are a fully integrated drug discovery through translational and early clinical development organization which exploits state-of-the-art in vitro, in vivo and ex-vivo models of Cancer biology and Immuno-oncology to identify and validate targets. We partner closely with colleagues in Translational Medicine, Informatics and Predictive Sciences and Early Clinical Development to generate biomarker and patient enrichment hypotheses to enable efficient decision making in early clinical trials. We are optimally positioned to complement the world-class translational expertise, biology and leading academic research centers in the area. Our Bristol Myers Squibb research site in Cambridge Crossing will help us continue to deliver on our mission, positioning the company and our scientists in the heart of a vibrant ecosystem of world-class science, innovation, and business opportunities. We are seeking an individual with oncology research experience to join the Translational Research team within the Oncology Thematic Research Center at Bristol Myers Squibb in Cambridge, MA. The qualified candidate is a highly motivated, engaged, and organized scientist that can thrive in a highly matrixed organization. This role will support translational research lab-based activities from the stage of development candidate optimization through Proof-of-Concept clinical trials. This individual will play an important role in supporting the development and execution of translational strategies for early phase oncology assets, enabling the development of transformative cancer therapies for patients.

Requirements

• Bachelor’s Degree 5+ years of academic and / or industry experience
• Or Master’s Degree 3+ years of academic and / or industry experience
• Or Ph.D. or equivalent advanced degree in the Life Sciences
• No experience required

Nice To Haves

• Bachelor’s or Master’s Degree with 5+ years of industry experience.
• Oncology translational research experience is highly desired.
• Experience in oncology and cancer immunology.
• Proficient in translational research encompassing biomarker identification, PK/PD and efficacy correlations, and dose estimation
• Experience designing and validating novel biomarker assays for proof-of-concept, suitable for deployment in early-phase clinical trials.
• Collaborate closely with fellow translational research scientists, actively sharing expertise and ensuring smooth information exchange across programs and portfolios to strengthen teamwork and drive scientific advancement.
• Experience performing analysis of protein, DNA, and RNA samples using a variety of methodologies including but not limited to: flow cytometry, MSD/ELISA, Western blot, qPCR, and functional assays.
• Ability to effectively collaborate with internal and external partners (e.g. CROs, specialty labs, etc.)
• Ability to be flexible with changing priorities while working in a cross functional team.

Responsibilities

• Develop biomarker, pharmacodynamic and target engagement assays.
• Use current and new techniques to characterize drug mechanism of action and resistance.
• Have familiarity with commonly utilized in vitro oncology and cancer immunology models and assays.
• Experience performing laboratory work, including cell culture and isolation of primary immune cells.
• Execute experiments independently, troubleshoot as needed, analyze, interpret and discuss data.
• Design and execute preclinical studies to inform indication selection, patient enrichment, rational combination strategies, and selection of biospecimen collection timepoints
• Have excellent time management skills and the ability to conduct experimental work independently, with accurate, detailed record-keeping.
• Display excellent communication, presentation and interpersonal skills.

Benefits

• Health Coverage: Medical, pharmacy, dental, and vision care.
• Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
• Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
• Work-life benefits include: Paid Time Off US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees) Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays Based on eligibility, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day. All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Number of Employees: 5,001-10,000 employees