Scientist II or Sr. Scientist, Analytical Development

Lyell Immunopharma • Seattle, WA

1d • $140,000 - $180,000

About The Position

The Scientist II or Sr Scientist, Analytical Development (AD) will be responsible for leading a newly formed product characterization team within Analytical Development. The role and responsibilities would include but are not limited to characterizing drug products from Lyell’s manufacturing facility using flowcytometry, cell based and molecular methods to facilitate manufacturing success, process improvement, immunological interpretations and driving clinical correlations. The successful candidate will be responsible for leading the team and open to hands-on bench work. The role will encompass driving projects across various Lyell programs in close collaboration across TechOps, Research, Translational and Biometrics teams. The Scientist in this role will work closely with other members of the AD group to support development of characterization assays and transfer them to the product characterization team, mentor team members, review data, maintain high quality ELNs and contribute to IND filings.
The successful candidate will have expertise in cellular immunology, flowcytometry, cell-based and molecular assays with analytical testing methodologies and an understanding of the technological requirements to execute on testing and characterization needs of a cellular therapy company.

Requirements

• Scientist II - A minimum of 11 years of experience in immunology / cell biology, plus a Bachelors or 9 years of experience plus a Masters degree
• Sr. Scientist I - A minimum of 10 years of extensive experience in immunology/ cell biology, plus a Phd
• Well versed in wide variety of analytical techniques such as cytotoxicity assays, flowcytometry, cytokine release assays, cell counting, short term cell culture and other applicable methods.
• Experience in analytical development, cGMP QC testing and implementation of new technologies in a regulated environment.

Nice To Haves

• Previous people management experience preferred
• Experience with assessment of new technologies in a fast-paced, learning organization preferably in a cross-functional setting where impact of new technologies is evaluated across research, development, and commercial organizations.
• Prior experience in cell therapy development preferred.
• Must have excellent oral and written communication skills
• Proven ability to work independently and collaboratively among cross-functional teams
• Ability to work efficiently, prioritize workflow, meet deadlines and balance competing priorities
• Excellent analytical skills and technical expertise

Responsibilities

• Design, develop, execute, and document flow cytometry/cell/molecular based analytical methods for product characterization and investigations.
• Support product characterization activities, including comparability assessments in support of product life cycle management.
• Partner in the transfer of qualified assays within AD and to QC, and support assay validation and investigations.
• Develop and deliver scientific presentations, prepare clear and concise technical reports, participate in project teams as needed.
• Participate in the evaluation of new analytical technologies and their implementation.
• Provide analytical support to cross-functional project teams.
• Revise, review, and author assay standard operating procedures and ELNs.
• Contribute to building a culture that encourages continuous learning, improvement, and innovation, and encourages team members to expand their technical skill base.

Benefits

• Lyell offers its employees a range of compensation and benefits.
• The salary range for this position is $140,000 to $180,000, annually, with the opportunity to earn an annual bonus.
• Employees are also eligible to participate in Lyell’s Equity Incentive Plan.
• Our Employee Benefits program is extensive and includes subsidized medical, dental and vision plans from your first day of employment, FSA, Company provided Life and AD&D Insurance as well as STD and LTD Insurance, ESPP, a 401(k) Plan with Company match, mass transit commuter benefits, cell phone reimbursement and a range of supplemental benefits that you may choose to elect.
• Our paid time-off benefits currently include 18 days’ vacation, 9 day’s sick leave, 8 observed holidays as well as a floating holiday.
• We also have a summer and a winter office shutdown.
• Our Employee Benefits program is extensive and includes subsidized medical, dental and vision plans from your first day of employment, FSA, Company provided Life and AD&D Insurance as well as STD and LTD Insurance, ESPP, a 401(k) Plan with Company match, mass transit commuter benefits, cell phone reimbursement and a range of supplemental benefits that you may choose to elect.
• Our paid time-off benefits currently include Flex Time off, sick leave, 8 observed holidays as well as a floating holiday.
• We also have a winter office shutdown.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Number of Employees: 251-500 employees