Scientist/Sr. Scientist - Analytical Development
About The Position
SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials. SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company's success. The Analytical Development Scientist /Sr. Scientist will be a core contributor to the development and characterization of antibody-based therapeutics. The scientist will design and implement analytical methods for early- to mid-stage development, with a focus on UPLC, CE, and binding assays. The scientist will also contribute to early-stage protein formulation development work. This is a hands-on lab role ideal for a PhD-level scientist who thrives in a dynamic, high throughput setting and is proficient in working cross-functionally. This is a full-time onsite position at our Redmond, WA location.
Requirements
- PhD in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences, or related discipline.
- 0–3+ years of relevant industry experience (biotech/pharma) in biologics analytical development and demonstrate strong teamwork.
- Solid understanding of antibody structure, post-translational modifications, and critical quality attributes (CQAs).
- Comfortable working in a dynamic environment with shifting priorities and evolving needs.
- Excellent communication, organization, and problem-solving skills.
Nice To Haves
- Hands-on experience with antibody binding assays (e.g., ELISA, SPR or BLI).
- Strong technical background in HPLC/UPLC and CE techniques for therapeutic proteins.
- Experience in tech transfer, method qualification, or early GMP readiness.
- Familiarity with software platforms like JMP, Empower, SoftMax Pro, or ForteBio Data Analysis.
- Passion for working in a mission-driven environment and building from the ground up.
Responsibilities
- Develop and execute robust analytical methods using UPLC (SEC, IEX, RP), CE (CE-SDS, cIEF), and binding assays (ELISA, BLI) to support antibody characterization. Maintain good documentation for all studies.
- Support cell line development, process development, formulation screening, comparability, and stability studies.
- Analyze, interpret, and communicate data to project teams in a timely and scientifically rigorous manner.
- Collaborate with upstream, downstream, and formulation scientists in an integrated CMC environment.
- Author high-quality technical reports, method protocols, and contribute to regulatory documentation.
- Evaluate new analytical technologies and help build internal capabilities as the company scales.
- Contribute to establishing a phase-appropriate analytical control strategy for lead candidates.
- Wear multiple hats, bring solutions, and help shape the analytical infrastructure as the company grows.
Benefits
- SystImmune offers a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and MORE.
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What This Job Offers
Job Type
Full-time
Career Level
Entry Level
Education Level
Ph.D. or professional degree
