Scientist I, Medicinal Chemistry

Neomorph•San Diego, CA

9h•Onsite

About The Position

Who we’re looking for: You are a highly collaborative, talented and motivated medicinal chemist, with a strong understanding of modern synthetic organic chemistry methods. You thrive in a multi-disciplinary team environment and are looking for an opportunity to work alongside leaders in the field of targeted protein degradation, where you are empowered to enable drug discovery programs and explore new aspects of this emerging and compelling science. Role and responsibilities: Contribute to projects as a synthetic and medicinal chemist aiding in driving projects from inception, through hit finding and lead optimization, to candidate selection and clinical development. In this lab-based role, you will impact from the bench through designing and executing multistep syntheses of complex small molecules while characterizing intermediates and final products. Leverage SAR insights, as well as structure‑ and ligand‑based design techniques, and optimize pharmacological properties Be a team player to enable chemistry for project teams and/or generate advanced building blocks for team use. Have the opportunity to manage external chemistry resources focusing on problem solving and target prioritization. Contribute to patents and scientific publications. Work within mandated laboratory safety policies and practices and maintain an electronic notebook to company standards

Requirements

Ph.D. in synthetic organic chemistry or related discipline, or M.S. with 5+ years industry experience, or B.S. with 10+ years industry experience.
Proven ability to design and synthesize high‑impact small molecules that move drug discovery programs toward critical decision points.
Demonstrated in depth knowledge of modern organic synthetic methods, purification and analytical techniques.
Demonstrated knowledge of medicinal chemistry including multiparameter optimization efforts.
Strong collaboration and communication skills.

Nice To Haves

The ideal candidate is familiar with both structure and ligand based small molecule optimization paradigms.

Responsibilities

Contribute to projects as a synthetic and medicinal chemist aiding in driving projects from inception, through hit finding and lead optimization, to candidate selection and clinical development.
In this lab-based role, you will impact from the bench through designing and executing multistep syntheses of complex small molecules while characterizing intermediates and final products.
Leverage SAR insights, as well as structure‑ and ligand‑based design techniques, and optimize pharmacological properties
Be a team player to enable chemistry for project teams and/or generate advanced building blocks for team use.
Have the opportunity to manage external chemistry resources focusing on problem solving and target prioritization.
Contribute to patents and scientific publications.
Work within mandated laboratory safety policies and practices and maintain an electronic notebook to company standards

Benefits

Industry competitive compensation
Annual target bonus
Stock options
401K plan
Career advancement opportunities
Monthly town halls to share business and scientific updates
Work Hard, Stay Well
Comprehensive medical, dental, and vision plans for employees and their dependents
Health and Dependent Care FSA and HSA Plan with monthly Neomorph contribution
Employee Assistance Program
10 holidays + Winter Shutdown + 3 weeks of vacation time with additional accruals after 2nd year of employment, separate sick leave.
Supplemental pay for Pregnancy Disability Leave
Paid Parental Leave for employees with a newborn child or a child placed with them for adoption or foster care
Lifestyle
Casual work environment
Volunteer days off each year to spend time contributing to causes you care about
Flexible work schedule
Access to onsite gym
Onsite space to store your bicycle (or surfboard)
Have Fun!
We believe in work/life balance and Fun is at the core of our Core Values. In addition to department and company happy hours, we have regular company-wide and department lunches and social events (ie Padres games, summer picnic, holiday party, bring your kids to work day).