Scientist I, Immuno-Oncology & Cell Therapy PC 1608

Miltenyi Biomedicine • Gaithersburg, MD

26d • $86,783 - $102,109

About The Position

As a member of the Research and Development team, you will have the opportunity
to play a key, hands on role in performing scientific experiments that lead to
the next generation of CAR-T cell therapies. You will be responsible for human
immune cell isolation and culture, tumor cell line culture and maintenance,
carrying out advanced methods of T cell activity analysis, and using gene
transfer techniques including lentiviral gene vector design and use and
LNP-based gene delivery. These research and therapeutic T cell development
pathways utilize new and innovative technologies developed in-house, such as
flow cytometry, advanced imaging, and automated cell processing in static and
active cultures. The incumbent will have the opportunity to interact with a
highly diverse and collaborative team of scientists focused on research and
development of novel cell and gene therapies, to contribute to scientific
publications, development of clinic-ready and commercial cell therapy products,
and to grow professionally.

Requirements

• PhD or MD, preferably with a postdoctoral training and strong expertise in immunology, gene vector biology, cell isolation and expansion techniques.
• Cell culture and flow cytometry experience.
• Expertise in T cell functional assays.
• Familiarity with DNA sequence databases, flow cytometry software, statistical software packages for data analysis and presentation.
• You are creative, goal-oriented and able to work both in independent and multidisciplinary situations. In addition, you welcome new challenges.
• Excellent communication skills and a proven track record in preparing scientific data for presentation.

Nice To Haves

• Experience in lentiviral gene vectors is a plus.

Responsibilities

• Culture and maintenance of primary human immune cells, leukemia and lymphoma cell lines, and cancer cell lines.
• Employ state of the art immune cell functional assays including flow cytometry, cytolytic and cytokine secretion analysis, metabolic assays, cell avidity measurement, and gene expression analysis.
• Perform both small-scale and large-scale CAR-T cell expansion.
• Employ novel gene vector and LNP-based gene modification. Experience in lentiviral gene vectors is a plus.
• Work independently and in in a team environment, effectively communicating results featuring precise data analytics.
• Other duties as assigned.

Benefits

• In addition to your salary, the Company offers a comprehensive benefits package, including health, vision, and dental insurance, as well as a 401(k) plan.
• All benefits are subject to eligibility requirements.
• Certain positions may also be eligible for additional compensation such as bonuses or commissions.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: Ph.D. or professional degree
• Number of Employees: 501-1,000 employees