Scientist, Analytical Sciences

AstraZeneca • Gaithersburg, MD

36d • Onsite

About The Position

Are you driven by a passion for science and eager to make a tangible impact on the world? At AstraZeneca, we transform scientific ideas into life-changing medicines, always putting patients first. If you're ready to think big, collaborate effectively, and explore the possibilities of science, then this opportunity is for you! Our Gaithersburg, MD facility is a hub of innovation, where over 3,500 experts work tirelessly to develop groundbreaking treatments. With state-of-the-art technology and vibrant lab spaces, we foster an environment of collaboration and creativity. Join us in pushing the boundaries of science and making a real difference in patients' lives. As a Scientist in Analytical Sciences, you will play a crucial role in the physicochemical analysis of biopharmaceutical products, including novel therapeutic proteins and monoclonal antibodies. Your responsibilities will encompass analytical method development, method qualification/transfer, unknown peak identification, degradation pathway analysis, and more. You will conduct lab experiments, collaborate with various development groups, prepare and review SOPs and reports, and contribute to regulatory submissions. Additionally, you will have the opportunity to publish and present your work in high-quality journals and conferences. AstraZeneca offers an inspiring environment where you can leverage your expertise to make a profound impact on patients' lives. Our dynamic approach encourages continuous learning and innovation, allowing you to explore new pathways and stretch your thinking. With countless opportunities for growth across our global Therapy Areas, you'll be part of a community that values collaboration and creativity. Here, every challenge is an opportunity to improve, driving us towards groundbreaking solutions that truly matter. Ready to take action? Apply now to join our team of dedicated scientists at AstraZeneca!

Requirements

• A bachelor or a master degree or equivalent in biology, chemistry, or related field.
• B.S. with 5+ years, M.S. with 3+ year
• In-depth knowledge in biochemical/biophysical analysis and characterization of proteins
• Strong background and hands-on experience in chromatographic techniques such as SEC, RP-HPLC, HILIC, IEX, and HIC
• Strong background and hands-on experience in electrophoretic techniques such as CE-SDS, CZE and icIEF, and SDS-PAGE
• Extensive knowledge of Openlab and Empower CDS Software
• Must be able to understand and apply complex and advanced chemical concepts in a laboratory setting and should have high aptitude for maintaining and troubleshooting lab instrumentation
• Ability to work in a highly matrixed structure and to interface and share ownership of projects with different groups within research and development
• Experience with analytical method transfer and validation
• Experience with Laboratory Information Management Systems (LIMS)
• Must have strong verbal and written communication skills

Nice To Haves

• High technical proficiency, scientific creativity, collaboration with others, and critical thinking
• Ability to independently determine methods and procedures on new assignments, and to mentor associate scientists
• Ability to conduct research project activities with minimal supervision
• Ability to plan project activities and meet timelines
• Familiarity with mass spec analysis of proteins, glycans, and oligonucleotides is an added benefit

Responsibilities

• physicochemical analysis of biopharmaceutical products, including novel therapeutic proteins and monoclonal antibodies
• analytical method development
• method qualification/transfer
• unknown peak identification
• degradation pathway analysis
• conduct lab experiments
• collaborate with various development groups
• prepare and review SOPs and reports
• contribute to regulatory submissions
• publish and present your work in high-quality journals and conferences

Benefits

• short-term incentive bonus opportunity
• eligibility to participate in our equity-based long-term incentive program (salaried roles) or to receive a retirement contribution (hourly roles)
• qualified retirement program [401(k) plan]
• paid vacation and holidays
• paid leaves
• health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Number of Employees: 5,001-10,000 employees