Scientist, ADC Biochemistry

BioNTech•Cambridge, MA

8d•Onsite

About The Position

BioNTech is developing novel Antibody-Drug Conjugates (ADCs), protein degraders and other targeted therapeutics for the targeted treatment of cancer with the goal of maximizing efficacy and minimizing toxic effects to patients. To achieve this goal ADCs and/or degraders will be prepared, evaluated in a battery of in vitro and in vivo assays, then based on results, improved therapeutics will be developed. Are you ready to make a significant impact in the oncology field? We are seeking a highly motivated and independent Scientist to join our ADC Innovation Unit in Cambridge, MA. Become a part of a multidisciplinary team of Global ADC Innovation Unit, supporting antibody-drug conjugate (ADC) research programs

Requirements

PhD with 3 plus years of experience, Master’s with 5 plus years, or Bachelor’s with 6 plus years of experience in a relevant field
Expertise in protein or antibody drug conjugation and characterization
Strong skills in protein expression, purification, and characterization
Experience in mammalian cell culture, including both adherent and suspension cells, transient protein expression, and cell-based assays
Proficiency with AKTA and HPLC systems
Familiarity with filtration operations, including bench-scale dead-end filtration and TFF
Competence in protein-based assays such as ELISA and MSD is advantageous
Strong teamwork and proactive communication skills
Self-driven and capable of working independently within a cross-functional team environment
Must be willing to work onsite at least four days a week

Nice To Haves

Previous experience in the biopharmaceutical industry is preferable but not mandatory
Hands-on experience with conjugation method development
Experience with site-specific conjugation or dual payload conjugations

Responsibilities

You will be responsible for working independently or collaboratively to ensure the timely generation and characterization of ADCs.
The ideal candidate is highly motivated, detail-oriented, productive, and able to autonomously conduct various experimental techniques while confidently presenting results to cross-functional teams.

Benefits

Medical, Dental and Vision Insurance
Life, AD&D, Critical Illness Insurance
Pre-tax HSA & FSA, DCRA Spending Accounts
Employee Assistance & Concierge Program (EAP) available 24/7
Parental and Childbirth Leave & Family Planning Assistance
Sitterstream: Virtual Tutoring & Childcare Membership
Paid Time Off: Vacation, Sick, Bereavement, Holidays (including Floating) & Year-End U.S. Shutdown.
401(K) Plan with Company Match
Tuition Reimbursement & Student Loan Assistance Programs
Wellbeing Incentive Platforms & Incentives
Professional Development Programs
Commuting Allowance and subsidized parking
Discounted Home, Auto & Pet Insurance