Researcher

University of Louisville • Aurora, CO

15h • $52,993 - $79,540

About The Position

The Pediatric Research Institute, Department of Pediatrics, University of Louisville School of Medicine, is seeking a Researcher supported by NIH grants. The selected candidate will study the molecular mechanisms underlying diabetes-induced cardiovascular complications. The laboratory uses a combination of state-of-the-art approaches which are integrated with primary cardiovascular cell cultures, cardiovascular organoids and transgenic techniques, as well as in vivo conditional inducible knock-out and knock-in animal models to elucidate the molecular mechanisms underlying diabetes-induced metabolic disorder and cardiovascular complications. The Researcher will prepare and conduct experiments, data analysis, interpretation and will write reports and manuscripts, as well as make presentations. This is a grant funded position with continued employment contingent on grant renewals. We are unable to sponsor or take over sponsorship of a work visa for this position.

Requirements

• Master's degree in a related field and two (2) years of relevant experience or the equivalent combination of education and experience.

Nice To Haves

• Self-motivated, productive PhD, MD or DVM.
• Strong background in molecular biology, cell biology, pathophysiology, cardiology, and pharmacology.
• Previous experience in working with metabolic syndrome-associated complication and chemotherapy-induced cardiotoxicity animal models and human organoid models including diabetic cardiomyopathy, atherosclerosis, diabetic nephropathy, and doxorubicin-induced cardiotoxicity.
• Previous experience in small animal ultrasound imaging (echocardiography), flow cytometry, primary cell culture, human iPSC, human organoids, lipid metabolism, radioactive isotope, transcriptome, single cell/nuclear and spatial RNA sequencing, and virus handling.
• Tissue culture of primary adipocytes, cardiomyocytes, tubule cells, and/or hepatocytes.
• Human iPSC culture and human organoids development
• Transgenic mice handling.
• Metabolic syndrome model induction and monitoring.
• Heart, blood vessel, kidney, and liver function evaluation.
• Histopathology of blood vessel, heart, kidney, and liver and specialized imaging software.
• Scientific report and proposal writing.

Responsibilities

• Conduct and organize all biochemical, physiological, morphological, and histochemical studies.
• Perform data collection and analysis and perform research and related tasks on specified projects.
• Write reports and manuscripts, as well as make presentations.
• Develop new techniques; organize and conduct statistical analysis of data generated from study results.
• Update research projections: and conduct research on past literature, monitor current research literature for relevant information. This includes peer-reviewed manuscripts of research abstracts at national and international meetings.
• Collect, edit, and present research outcomes.
• May recommend new ideas for ongoing lines of research and may interpret and advise faculty regarding extramural funding source guidelines and requirements.

What This Job Offers

• Job Type: Full-time
• Number of Employees: 5,001-10,000 employees