Research Technologist - Lomberk

Mayo Clinic•Phoenix, AZ

2d•Onsite

About The Position

Sets up and performs routine and established lab procedures in support of lab goals, grant commitments, i.e. assays, cell/tissue culture, animal studies, etc. Monitors results, reports unusual outcomes and suggests modifications. Collects, enters and summarizes data. Assists in the maintenance of lab equipment and supplies. Performs basic statistical data analysis; prepares tables/charts/graphs and assists in organizing data. Presents at research laboratory meetings and contributes to writing of manuscripts. Works under supervision and may perform some assignments independently as discussed and approved by Principal Investigator. This vacancy is not eligible for sponsorship/ we will not sponsor or transfer visas for this position. Also, Mayo Clinic DOES NOT participate in the F-1 STEM OPT extension program. Additional Information: The Lomberk Laboratory is seeking a Research Technician who takes pride in rigorous science and is eager to develop their skills within a collaborative, discovery-driven research environment. This position is well-suited for candidates looking to build a strong technical foundation in cellular and molecular biology while contributing to meaningful, translational research. About the Lab The Lomberk Laboratory investigates how epigenomic regulators, including chromatin-modifying enzymes and remodeling complexes, control gene expression programs downstream of oncogenic signaling, shape DNA damage responses, and drive disease progression in cancers such as pancreatic cancer. Our work spans mechanistic discovery to translational impact, using cell-based assays, patient-derived model systems, and mouse models to identify vulnerabilities that can be targeted therapeutically. Purpose Under general direction from laboratory leadership, the Research Technician will perform, optimize, and implement a variety of laboratory techniques and experiments to support the generation of high-quality data in a cellular and molecular biology research setting. The individual will analyze, summarize, and present data to a team of scientists and contribute to discussions guiding next steps in research projects.

Requirements

Has a background in biology, biochemistry, or a related field
Has experience with or familiarity in cell culture, protein assays, or other core molecular biology techniques
Demonstrates strong attention to detail, organization, and reliability in experimental work
Is comfortable assisting with mouse work and general laboratory responsibilities
Possesses strong written and verbal communication skills
Is motivated, collegial, and able to work effectively in a team-oriented environment
Is eager to learn and grow in a research setting

Responsibilities

Perform protein-based assays including immunoblotting, co-immunoprecipitation, and chromatin immunoprecipitation (ChIP) to interrogate epigenomic and signaling pathways
Execute biochemical approaches to characterize protein-protein interactions and structure-function relationships of epigenomic regulators
Maintain mammalian cell lines and execute functional cell-based assays
Perform pharmacological assays to assess cellular responses to targeted therapies, epigenetic modulators, and their combinations
Perform immunofluorescence microscopy and imaging-based assays to assess DNA damage responses, chromatin organization, and nuclear architecture
Perform standard molecular biology techniques in support of ongoing projects
Assist with laboratory mouse work, including colony maintenance, genotyping, and support of experimental studies
Execute established protocols and assist in optimizing and scaling experimental procedures as needed
Maintain accurate and organized records of experimental procedures and results
Support day-to-day laboratory operations, including reagent and media preparation, supply monitoring, inventory management, and ordering
Participate in laboratory meetings and contribute to the evaluation and interpretation of experimental data
Assist in preparation of figures, methods, and other materials for manuscripts and presentations