Research Technician – Fischer Lab

Dana-Farber Cancer Institute • Boston, MA

2d

About The Position

The Fischer Lab at Dana-Farber Cancer Institute is a Structural and Chemical Biology Lab that combines a broad range of laboratory techniques to study the pathways and protein complexes involved in the regulation of protein homeostasis often associated with human diseases, including cancer. Using our knowledge of the cellular degradation machinery, we use structure and computational guided approaches to develop and test new molecules that hijack the ubiquitin proteasome system for targeted protein degradation. Combining fundamental mechanistic insights with translational chemical biology research, we are pioneering new therapeutic avenues.
The Fischer lab (https://fischerlab.danafarber.org/) seeks a highly motivated individual to join the team as a RESEARCH TECHNICIAN, who will employ mass spectrometry-based technologies to assess the cellular proteome in response to external stimuli. This individual will be an important member of our core team and will work with technicians, scientists, postdocs and students on a variety of different research projects focused on targeted protein degradation as a novel therapeutic modality.
Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS, and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

Requirements

• Bachelor's Degree required with a major in biology or chemistry preferred
• A knowledge of information and techniques related to biology, chemistry or medicine is preferred
• Must have close attention to detail and consistent work habits
• Must have good time management
• Ability to work in a collaborative and team environment
• Excellent oral and written capabilities

Nice To Haves

• Understanding of statistical and computational methods is desirable
• Experience with R, MATLAB, or python and general computational abilities is preferred

Responsibilities

• Mammalian cell line management and ability to perform drug treatments and prepare samples from tissues and cells
• Prepares lab reagents and media
• Performs mass spectrometry sample preparation
• Operation and maintenance of standard lab equipment including HPLC’s, mass spectrometers
• Analyzes experimental data and interpret results to write reports, presentations, grant and publication preparation
• Maintains detailed notebook of all work-related activities
• Maintains and orders laboratory supplies
• Communicates with purchasing and may be responsible for negotiating with vendors
• Collaborates with other lab members for the development, modification and improvement of standard operating procedures

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Number of Employees: 5,001-10,000 employees