Research Specialist- School of Medicine, Hematology

Emory • Atlanta, GA

1d

About The Position

The Bhatt Laboratory in the Department of Hematology and Medical Oncology at Emory University School of Medicine is seeking a highly motivated Bioinformatician to join our dynamic research team. The successful candidate will work on high-impact translational research projects that bridge computational analysis with functional biology to identify novel therapeutic strategies for patients with blood cancers. The lab has established a strong track record of high-impact publications and has received prestigious funding from organizations including the American Cancer Society, European Molecular Biology Organization, American Association for Cancer Research, American Society of Hematology, and The Leukemia & Lymphoma Society. Lab website: https://www.bhatt-lab.com

Requirements

• Bachelor's degree in a scientific field OR equivalent combination of experience, education, and training.

Nice To Haves

• Bachelor's degree in Bioinformatics, Computational Biology, Data Science, Computer Science, Statistics, or related field with experience in bioinformatics analysis of genomics data (RNA-seq, scRNA-seq, ATAC-seq, or similar)
• Strong programming skills in R and/or Python
• Experience with next-generation sequencing data analysis tools and pipelines
• Proficiency in statistical analysis and data visualization
• Familiarity with high-performance computing environments and cluster job submission systems
• Experience with version control systems (Git/GitHub)

Responsibilities

• Under general supervision, performs a variety of defined research and laboratory tests and experiments according to prescribed protocols and assigned schedules.
• Sets up experiments as prescribed by a principal investigator.
• May be required to participate in laboratory maintenance activities such as sterilization and cleaning of equipment, ordering of supplies, inventory and media preparation.
• Maintains records, files and logs of work performed in laboratory notebooks and computer databases.
• Compiles data and records results of studies for publications, grants and seminar presentations.
• Employees in this classification may be required to work with, take specific precautions against and/or be immunized against potentially hazardous agents.
• Performs related responsibilities as required by principal investigator.
• Analyze large-scale multi-omics datasets including bulk and single-cell RNA sequencing, ATAC-seq, DNA sequencing, proteomics, and metabolomics data from AML patient samples and preclinical models
• Perform differential gene expression analysis, pathway enrichment analysis, and network analysis to identify key regulators of therapy resistance
• Analyze clonal evolution and lineage tracing data to map resistance trajectories during AML treatment
• Integrate functional genomics data (CRISPR screens) with transcriptomic and epigenomic datasets to identify therapeutic vulnerabilities
• Develop machine learning models to predict therapeutic response based on multi-omics features
• Build predictive algorithms for patient stratification using dynamic BH3 profiling data and molecular profiles
• Apply dimensionality reduction techniques and clustering methods to identify AML subpopulations with distinct resistance mechanisms

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level