Research Services Laboratory Science Entry Professional
About The Position
The lab of Dr. Sarah Clark, Assistant Professor in the Department of Otolaryngology, is seeking a highly motivated Professional Research Assistant for a part-time position on the University of Colorado Denver Anschutz Medical Campus in Aurora, CO. This position will be shared between Dr. Clark and Dr. Marika Orlov, an Instructor in the Pulmonary and Critical Care Division working in Dr. Clark’s lab. The Clark lab investigates host-pathogen interactions with a focus on innate immune responses to bacteria in the respiratory tract. We use both tissue culture and in vivo infection models to explore the impact of respiratory tract commensal and pathogenic bacteria on susceptibility to inflammation and secondary infection. Current projects are focused on how specific respiratory tract commensal bacteria improve defense against lung infection, and how viral co-infection causes long-term perturbations in immune defense to bacterial infections in the middle ear (otitis media). Dr. Orlov is a new Instructor whose research focuses on how antibiotics alter the gut microbiome, ultimately impairing defense against subsequent lung infections. Dr. Orlov is currently investigating dietary modifications as an intervention to improve lung infection defense after antibiotic treatment. The PRA will be responsible for planning and executing experiments under the direction of Dr. Clark and Dr. Orlov. The individual hired for this position will be expected to perform experiments, analyze and organize their data, and perform laboratory administrative duties. Training will be offered for any new or unfamiliar techniques by Dr. Orlov and other lab personnel upon starting the position.
Requirements
- Bachelor’s degree in biology, molecular biology, chemistry, genetics, immunology or related field
- A combination of education and related technical/paraprofessional experience may be substituted for the bachelor’s degree on a year for year basis.
- Applicants must meet minimum qualifications at the time of hire.
- Knowledge of basic laboratory techniques including safety procedures and techniques
- Ability to communicate effectively, both in writing and orally
- Ability to establish and maintain effective working relationships with employees at all levels throughout the institution
- Ability to interpret and master complex research protocol information
- Knowledge in the areas of Immunology and/or Bacteriology
Nice To Haves
- Master’s degree in biology, molecular biology, chemistry, genetics or related field
- Prior experience or background within an experimental or wet laboratory
- Experience with techniques including mouse handling, tissue culture, flow cytometry, PCR, and other molecular biology assays
- Experience with models of lung inflammation or infection
Responsibilities
- Handling of microbial cultures and tissue cultures with BSL2 level precautions
- Preparation of bacterial cultures for in vitro and in vivo infection assays
- Perform in vivo infection experiments including injections, infection monitoring, and tissue processing
- Perform in vitro infection experiments with human epithelial cell cultures
- Perform flow cytometry experiments
- Data analysis and maintenance of records in laboratory notebook and storage on OneDrive
Benefits
- The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.
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What This Job Offers
Job Type
Part-time
Career Level
Entry Level
