Research Senior Scientist, Lead Profiling

Takeda • Boston, MA

13d • Hybrid

About The Position

At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible to bring life-changing therapies to patients worldwide. Objective / Purpose: Takeda’s Lead Profiling team is building a new team of experienced, innovative, and collaborative researchers to partner with the Gastrointestinal and Inflammation (GI2) Drug Discovery Unit to design and run high throughput automated assays on state-of-the-art robotic platforms to drive an industry-leading portfolio of drugs for various gastrointestinal, autoimmune, and inflammatory diseases with high unmet medical needs. We seek a skilled Research Sr. Scientist to join our Lead Profiling and cross-functional discovery teams. Design and execute pre-clinical pharmacology strategies on fully automated robotic platforms to support candidate selection, accelerating clinical translation of impactful therapties for patients with inflammatory and autoimmune disorders Provide deep scientific expertise in the design and eexecution of miniaturized, high throughput assays for immunology/cellular pharmacology, acting as a subject matter expert across cross-functional teams Leverage state-of-the-art automation to streamline complex biology screening workflows and manage data across GI2 programs, in close collaboration with Takeda scientists and external partners

Requirements

• PhD degree in immunology/pharmacology with 2+ years industry experience, or MS with 8+ years’ experience, or BS with 10+ years of relevant experience in pharmaceutical/ biotech R&D.
• Strong expertise and depth of knowledge in complex cell-based assay development and screening technologies (e.g., Flow cytometry, AlphaLISA, TR-FRET, ELISA and etc).
• Extensive experience with state-of-the-art automation and assay miniaturization to streamline assay workflows.
• Significant experience leveraging high throughput data analysis platforms and LIMS systems for automated data analysis, QC and reporting
• Proven experience in developing and/or evaluating novel small molecule and biologics

Nice To Haves

• Foundational knowledge in enginnering and programming is highly desirable
• Stays current with emerging scientific literature, competitive landscapes, and innovative technologies

Responsibilities

• Develop and implement fully-automated screening workflows to support multiple programs in the GI2 portoflio
• Champion scientific integrity and rigor in data analysis, prepartion, and interpretation of detailed protocols/SOPs.
• Collaborate effectively within a matrixed structure, clearly communicate results, challenges, and impact through presentations and discussions with broad audiences.
• Integrate data from cross-functional teams to drive decision-making.
• Think independently and creatively to explore novel drug discovery approaches to create therapies for patients suffering from immune driven disorders.

Benefits

• U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others.
• U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: Ph.D. or professional degree
• Number of Employees: 5,001-10,000 employees