Research Scientist- CryoEM Facility
About The Position
RESEARCH SCIENTIST, CRYOEM FACILITY, Biology, will be supporting a diverse and expanding research community in cryogenic sample preparation, imaging, and data analysis and will train and support users in specimen preparation, data collection, and cryoEM/cryoET workflows; maintain and calibrate instruments; assist in collaborative projects; and help shape next-generation techniques in structural biology including leading the integration of the HydraBio system for advanced in situ studies using fluorescence-guided targeting. Located within MIT.nano, the facility features cutting-edge instrumentation, including a Titan Krios (BioQuantum-K3), Talos Arctica (Falcon3EC/K3), and an Aquilos cryo-FIB/SEM (soon to be upgraded to a HydraBio plasma FIB/SEM with Delmic METEOR fluorescence microscope), along with Chameleon and Vitrobot vitrification systems and robust computational infrastructure. Responsibilities include user training and mentoring (~35%), facility operations and administration (~30%), collaborative work and staff-assisted usage (~20%), equipment maintenance (~10%), and community engagement (~5%).
Requirements
- Ph.D. in biochemistry, structural biology, biophysics, or a related discipline
- Demonstrated expertise in transmission electron microscopy (TEM) and/or scanning electron microscopy (SEM)
- Familiarity with cryogenic sample preparation methods
- Strong troubleshooting, organizational, and interpersonal skills
- Ability to work independently while balancing the needs of a multi-user facility
- Commitment to training and supporting a diverse scientific community
Nice To Haves
- Four+ years of research experience in biological electron microscopy
- Experience with cryo-FIB milling and lamella preparation
- Background in SPA, cryo-electron tomography, or related data processing workflows
- Experience identifying and diagnosing microscope or equipment performance issues
- Proficiency with computational tools for cryoEM data analysis
- Experience with Python, Linux, or HPC environments
- Experience in a multi-user or shared research facility
Responsibilities
- User training and mentoring (~35%)
- Facility operations and administration (~30%)
- Collaborative work and staff-assisted usage (~20%)
- Equipment maintenance (~10%)
- Community engagement (~5%)
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
Industry
Educational Services
Education Level
Ph.D. or professional degree
Number of Employees
5,001-10,000 employees
