Research Scientist & Antibody Computational Analysis

Brigham and Women's Hospital•Cambridge, MN

63d•$80,000 - $105,000•Onsite

About The Position

Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. The DeKosky Laboratory for Immune Engineering and Drug Discovery (www.dekoskylab.org, Google Scholar: http://scholar.google.com/citations?user=z6TwVlwAAAAJ&hl=en) is hiring a scientist to advance computational drug design and discovery, including the use of artificial intelligence (AI) and machine learning (ML) techniques. The hired candidate will focus on computational aspects of immune repertoire analyses of antibody functional screening data. These efforts will advance methods for rapid machine learning-based antibody drug design while developing new and improved antibody drug products. We are looking for enthusiastic individuals that are curious about computational drug discovery and immunology, and want to participate in the exciting world of diving deeply into understanding how computational data and molecular design can be applied to discovery new drugs and fight diseases. The selected candidate will join a dynamic research team at the forefront of antibody engineering. These projects are fully funded by the several organizations, including the US National Institutes of Health and collaborative projects with the Bill and Melinda Gates Foundation, with several ongoing efforts and new projects ready to begin. The Ragon Institute is an internationally renowned immunology-focused research center located in Kendall Square, Cambridge, Massachusetts, and with affiliations with MGH, Harvard, and MIT. This position is ideal for individuals who are interested in launching a career as biomedical research leaders in either academia or industry. Successful candidates will be immersed in a rich scientific community and become experts in advanced high-throughput drug development and establish cutting-edge drug screening approaches while being a part of a supportive, highly collaborative research environment with state-of-the-art facilities. The hired candidate will also be an affiliate of MIT, with access to MIT campus research resources and community facilities. Job Summary In consultation with their Principal Investigator (PI), undertake and execute a program of scientific study culminating in publication. Drives research projects scientifically and determines the course of research as evidenced by leadership, obtaining funding, writing, or other recognition. May not necessarily receive independent resources; however, their contribution is essential to the conceptual/scientific success of the project. They assist their PI in the training and supervision of other laboratory personnel and in a wide variety of administrative tasks, as necessary.

Requirements

Doctorate Related Field of Study required
Previous Research experience (inclusive of graduate and postdoctoral experience) 5-7 years required
Excellent research skills.
Demonstrated evidence of specific scientific competence in field.
Demonstrated broad knowledge of field.
Evidence of potential for scientific creativity and original though.
Able to exercise independent judgment and leadership.
Ability to contribute to publications.

Responsibilities

Makes proficient intellectual contributions to scientific strategies of the group/lab and plays a leadership role by acting as subject matter authority in the field.
Contributes to the design and execution of experiments and/or research projects.
Exercises judgment in selecting methods and technologies to obtain results.
May collaborate with external researchers and/or receive external project funding support.
Presents results and prepares publications.
May assist PI in the training and supervision of other staff.

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