Computational Research Scientist

St. Jude Children's Research Hospital•Memphis, TN

53d

About The Position

Join the Zhou lab ProteinPaint team (https://proteinpaint.stjude.org/team/) to contribute to the development of an open-source platform for biomedical data visualization, analysis and sharing. The ProteinPaint began as a cancer mutation visualization tool (https://pubmed.ncbi.nlm.nih.gov/26711108/), and is now an umbrella platform spanning GenomePaint (https://pubmed.ncbi.nlm.nih.gov/33434514/), Neuro-Oncology portal (https://pubmed.ncbi.nlm.nih.gov/41190809/), Survivorship Portal (https://pubmed.ncbi.nlm.nih.gov/38593228/), NCI Genomic Data Commons (https://portal.gdc.cancer.gov/, paper in preparation), and ASH HematOmics Program (https://proteinpaint.stjude.org/ashop/, paper in revision). A portfolio of the software features are showcased at https://proteinpaint.stjude.org/. Our software development focuses on multi-data-modality support, interoperability for data analysis, accountability with scientific rigor, and ease of access through AI chatbot. Along with continuous efforts to harden software features, ProteinPaint aims to support molecular and clinical data integration needs in cutting edge research. Fields of application include cancer genomics, single-cell omics, oncology, pharmacogenomics, population science, and public health. The applicant should be dedicating to a career of software development in genomics and general biomedical research. PhD in cancer, bioinformatics or relevant biological sciences is required. Proficiency in full-stack web development is required, including Linux, JavaScript, Node.js, R, Python, Rust, SQL and AI, along with knowledge in software testing, DevOps and Continuous Integration. While on the team, the new hire will work alongside other developers and PhD scientists and contribute to ongoing projects and have the opportunity to lead high-profile projects and give presentations or author scientific papers. Job Responsibilities: Lead computationally focused scientific research projects with moderate supervision from their PI. Provide inputs regarding analytical approaches, set up analyses, and can develop new computational research methods with input from PI. Identify, process, organize, summarize, review, and report relevant data. Draft a manuscript and work through the submission and review process with input from the PI, as directed. Instruct and provide guidance to other staff in basic computational research techniques and procedures. (In the case of recent Ph.D. graduates, this position can be considered equivalent to a mentored postdoctoral position.) Perform other duties as assigned to meet the goals and objectives of the department and institution. Maintains regular and predictable attendance.

Requirements

PhD in cancer, bioinformatics or relevant biological sciences is required.
Proficiency in full-stack web development is required, including Linux, JavaScript, Node.js, R, Python, Rust, SQL and AI, along with knowledge in software testing, DevOps and Continuous Integration.
Bachelor's degree in Bioinformatics, Molecular Biology, Biochemistry, Computer Science, or related field required.
Bachelor's degree and 6+ years of relevant experience.
Master's degree and 4+ years of relevant experience (OR) PhD with no experience.
1-2 first author papers IF >5 (or equivalent contribution to other research outputs).

Nice To Haves

Prior experience in computational research techniques preferred.
Experience in project coordination, maintenance, and other research support activities preferred.

Responsibilities

Lead computationally focused scientific research projects with moderate supervision from their PI.
Provide inputs regarding analytical approaches, set up analyses, and can develop new computational research methods with input from PI.
Identify, process, organize, summarize, review, and report relevant data.
Draft a manuscript and work through the submission and review process with input from the PI, as directed.
Instruct and provide guidance to other staff in basic computational research techniques and procedures.
Perform other duties as assigned to meet the goals and objectives of the department and institution.
Maintains regular and predictable attendance.

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