Research Lab Tech I, Pathology

Mass General Brigham • Boston, MA

1d • Onsite

About The Position

Join the Santagata Lab at Brigham and Women’s Hospital (BWH) as a Technical Research Assistant I. This role involves using cutting-edge molecular tissue imaging and quantitative assay methods to study tumor development, therapy resistance, and disease mechanisms in patient samples across various cancers. It offers an opportunity to work at the intersection of biological chemistry, molecular imaging, and clinical research, contributing to the development of new cancer therapies and diagnostics. The position requires close collaboration with Dr. Peter Sorger’s multidisciplinary team at Harvard Medical School’s (HMS) Laboratory of Systems Pharmacology (LSP) and other research initiatives. You will engage with a network of scientists, physicians, chemists, and computational biologists across multiple institutions, contributing to research that informs innovative clinical trials for various tumors and investigating disease mechanisms to support biomarker and drug development. Opportunities also exist to participate in studies of pulmonary and renal diseases. This role provides hands-on experience with high-dimensional pathology imaging, molecular assay development, data processing, computational analysis, and visualization, contributing to high-impact translational research.

Requirements

• Bachelor’s degree in a quantitative discipline, such as chemistry, biological chemistry, chemical biology, biophysics, biomedical engineering, or a related field
• Demonstrated interest in biomedical research, molecular measurement, and human disease
• Willingness to commit to a two-year position and grow in a dynamic research environment
• Strong background in biochemistry or biological chemistry, including understanding of protein structure–function relationships, antibody–antigen interactions, and molecular binding principles
• Strong communication skills
• Ability to work both independently and collaboratively within a multidisciplinary research team

Nice To Haves

• Experience or strong interest in microscopy, molecular or biochemical assays, quantitative biology, or data analysis
• Familiarity with or interest in quantitative image analysis and data science tools (e.g., Python, R, MATLAB, ImageJ)

Responsibilities

• Use cutting-edge molecular tissue imaging and quantitative assay methods to study tumor development, therapy resistance, and disease mechanisms in patient samples across a range of cancers
• Contribute to the development of new cancer therapies and diagnostics
• Collaborate closely with Dr. Peter Sorger’s multidisciplinary team at Harvard Medical School’s (HMS) Laboratory of Systems Pharmacology (LSP)
• Collaborate with members of Ludwig Cancer Research, the David Liposarcoma Research Initiative, the Bertarelli Rare Cancer Initiative and the Pituitary Neuroendocrine Tumor Translational Research (BioPitNeT)
• Engage with a vibrant network of scientists, physicians, chemists, and computational biologists across institutions including BWH, HMS, Massachusetts General Hospital, Dana-Farber Cancer Institute, Boston Children’s Hospital, and the Ludwig Center at Harvard, as well as collaborators nationwide
• Contribute directly to research that informs innovative clinical trials for immunotherapy and targeted therapies for sarcomas, gliomas, carcinomas, and neuroendocrine-related tumors
• Investigate disease mechanisms and pharmacodynamics (PD) to support biomarker and drug development
• Participate in studies of pulmonary and renal diseases
• Gain hands-on experience with high-dimensional pathology imaging, molecular assay development, data processing, computational analysis, and visualization
• Contribute to high-impact translational research that can change how cancers and other diseases are diagnosed and treated

Benefits

• Competitive base pay
• Comprehensive benefits
• Career advancement opportunities
• Differentials, premiums and bonuses as applicable
• Recognition programs designed to celebrate your contributions and support your professional growth

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level