Research Fellow - PC- General Internal Medicine

Mayo Clinic•Rochester, MN

16h

About The Position

The Mayo Clinic Division of General Internal Medicine is seeking a highly motivated Postdoctoral Fellow to partner directly with the physician leader of our Longevity Research Program. The fellow will oversee ongoing studies and catalyze new, high-impact research focused on disease prevention, metabolic health, and biological aging within the Division of General Internal Medicine. This role is ideal for a scientist-physician or PhD-trained researcher who thrives in translational research, cross-disciplinary collaboration, and rigorous methodology About the Program The Longevity Research Program within General Internal Medicine integrates preventive imaging, metabolic phenotyping, aging biomarkers, and genomics to develop actionable, patient-centered models of healthspan extension. We emphasize rigorous methods, data-driven decision-making, and equitable implementation in clinical practice.

Requirements

PhD in Epidemiology, Genomics/Computational Biology, Nutrition/Metabolism, Biostatistics, Biochemistry, Physiology, or related field.
Knowledge of research methods, including study design, protocol writing, IRB processes, and patient consent.
Demonstrated experience in clinical/translational research with strong methodological grounding.
Proficiency in statistical programming (e.g., R, Python, SAS) and data management.
Record of peer-reviewed publications commensurate with training stage.
Excellent written and verbal communication skills; proven ability to work in multi-disciplinary teams.
Able to learn new and use new computer programs

Nice To Haves

Experience with imaging research (MRI), advanced biochemical analyses (NMR), aging biomarkers (epigenetic clocks), and/or genomics (PRS).
Familiarity with machine learning and risk prediction modeling.
Prior success with grant writing (e.g., NIH F/K series, foundation awards).
Working knowledge of REDCap and electronic health records (EHR) for cohort development.

Responsibilities

Research Leadership & Oversight Lead day-to-day execution of active projects, including protocol adherence, recruitment, data collection, analysis, and dissemination.
Coordinate multi-disciplinary teams (clinical investigators, research coordinators, statisticians, data engineers) to achieve milestones on time and on budget.
Study Design & Innovation Develop new research proposals aligned with program priorities in longevity science; write protocols, IRB submissions, and grant applications.
Apply cutting-edge methods (e.g., machine learning, multi-omics integration) to address clinically meaningful questions.
Data Management & Analysis Build and maintain high-quality datasets; ensure data integrity, reproducibility, and compliance with institutional and federal regulations.
Collaborate closely with biostatistics and informatics partners.
Scholarly Output Lead and co-author manuscripts in biomedical journals.
Present findings at national/international meetings.
Contribute to white papers, clinical practice guidance, and knowledge translation.
Regulatory & Compliance Prepare and manage IRB submissions, amendments, and continuing reviews.
Uphold Good Clinical Practice (GCP), HIPAA, and institutional policies.
Mentorship & Team Culture Mentor junior trainees (students, residents, research coordinators) in methods and rigor.
Foster an inclusive, collaborative environment.