Research Fellow: HTE Medicinal Chemistry
About The Position
Biogen is one of the world’s leading biopharmaceutical companies, with a focus on developing therapies for serious conditions in neurology, immunology, and rare diseases. We are committed to research that uncovers the underlying biology of complex diseases. The High-throughput Experimentation for chemistry (HTE) platform within the Medicinal Chemistry group at Biogen is seeking a Research Fellow to conduct parallel microscale chemistry for reaction screening, optimization, and compound synthesis. The Research Fellow will design, develop, and apply novel synthetic methodologies to create automated high-throughput workflows for our reaction optimization and library synthesis capabilities. The Research Fellow role at Biogen is an 18-month position designed to provide a unique opportunity for scientists to gain exposure to drug discovery and development, high-throughput experimentation, laboratory automation, and train in an industry research setting. In this role, you will collaborate with internal drug discovery programs to deliver high-value targets through HTE.
Requirements
- Ph.D. in Organic Chemistry, with 0-1 years of experience.
- Excellent knowledge of synthetic organic chemistry.
- Expertise in techniques related to synthesis, purification, and characterization of organic compounds.
- Must have liquid chromatography and mass spectrometry experience specifically applied to reaction monitoring.
- Must be able to independently design, plan, execute and interpret parallel, data-driven, experiments.
- Demonstrated track record of publications, and/or scientific presentations.
- Should be able to work in a multidisciplinary team.
- Excellent oral and written communication skills.
Nice To Haves
- Familiarity with high-throughput experimentation (HTE)
- Familiarity with laboratory automation
- Automated liquid handlers
- Automated solid handlers
- Experience with preparative HPLC
Responsibilities
- Design production workflows for high-throughput experimentation in both reaction optimization and parallel medicinal chemistry with a focus on automation.
- Utilize our lab's modern chemistry equipment (UPLC-MS, automated solid and liquid handling, prep-HPLC, gloveboxes, and NMR).
- Attend project meetings and learn how to apply HTE reaction optimization and parallel synthesis to provide value for drug discovery projects.
- Present results both internally and externally via publications and/or conference presentations
Benefits
- Medical, Dental, Vision, & Life insurances
- Fitness & Wellness programs including a fitness reimbursement
- Short- and Long-Term Disability insurance
- A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
- Up to 12 company paid holidays + 3 paid days off for Personal Significance
- 80 hours of sick time per calendar year
- Paid Maternity and Parental Leave benefit
- 401(k) program participation with company matched contributions
- Employee stock purchase plan
- Tuition reimbursement of up to $10,000 per calendar year
- Employee Resource Groups participation
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What This Job Offers
Job Type
Full-time
Career Level
Entry Level
Education Level
Ph.D. or professional degree
