Research Associate

Ochre BioNew York, NY
8d$80,000 - $100,000Onsite

About The Position

We are looking for a talented and highly motivated Research Associate to join the Ochre Bio Team in NYC on an exciting journey to support the development of advanced RNA medicines for one of the most pressing healthcare challenges of our time. Ochre’s New York site is a highly unique organ perfusion lab that deep phenotypes human livers perfused on machines, to study their responses to advanced RNA therapies. Deep phenotyping includes: tissue imaging, blood and tissue functional studies, single-cell sequencing, and precision-slice culture of liver biopsies. This role generates the data coming out of Ochre’s liver perfusion lab. You will be expected to assist liver perfusion and process assays and imaging. You will report to the Head of Late Validation (the site head), working closely with the perfusion team to ensure robust data. The nature of the role will require regular evening and weekend work (additional compensation).

Requirements

  • BSc degree or higher in a biological science or similar field of study
  • ​​Significant wet lab experience in either an academic or industry setting
  • Ability to work in a fast paced environment where you have been expected to rapidly produce, analyze and present results
  • Experience with molecular and cellular techniques
  • Strong expertise with lab-based assays such as qPCR, western blots, cell-based assays and flow cytometry
  • Experience with cell and tissue culture
  • Strong organizational skills, with the ability to prioritize tasks effectively
  • Methodical approach to work and record keeping
  • Able to handle specimens using aseptic techniques
  • Ability to work in a fast-paced environment
  • High-level of attention to detail, with the ability to follow complex protocols
  • Excellent interpersonal skills

Nice To Haves

  • Prior research experience in liver biology
  • Clinical research experience
  • Liver perfusion or liver lab tech experience
  • Comfortable with histology (sample preparation and staining)
  • Ability to analyze and present data using R

Responsibilities

  • Sample processing and generation of phenotyping data including tissue imaging, blood and tissue functional studies and sequencing
  • Executing state of the art phenotyping strategies (assays, histology, RNA and protein readouts)
  • Analyze, review and interpret results
  • Assisting with setting up human liver perfusions, monitoring of livers during perfusion, problem solving and responding to poor liver function, collecting samples, and preparing samples for phenotyping (full training will be provided)
  • Actively collaborate and communicate with other members of Ochre Bio across all three sites (US, UK & Taiwan)
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