Research Associate II Proteomics

Allen Institute for Brain Science•Seattle, WA

64d•Hybrid

About The Position

The mission of the Allen Institute is to understand the principles that govern life and to advance health. Our creative and multi-dimensional teams focus on answering some of the biggest questions in bioscience. We accelerate foundational research, catalyze bold ideas, develop tools and models, and openly share our science to make a broad, transformational impact on the world. The mission of the Allen Institute for Brain Science is to accelerate the understanding of how the human brain works in health and disease. Using a big science approach, we generate useful public resources, drive technological and analytical advances, and discover fundamental brain properties through the integration of experiments, modeling, and theory. The Allen Institute for Brain Science is seeking a Research Associate who will be part of a multidisciplinary team within the newly formed Proteomics Program. The successful candidate will be a member of the Proteomics team, which produces and analyzes large-scale cell-type specific proteomics data from primary mouse brain tissue to help characterize subcellular compartments within neuronal and non-neuronal cell types in the brain. The candidate will play a role in collecting, processing, and analyzing acquired proteomics data and make improvements to existing experimental protocols, analysis pipelines, and help develop new ones. They may also assist in sharing data with internal and external collaborators. At the Allen Institute, we believe that science is for everyone and should be open to everyone. We are dedicated to combating biases and reducing barriers to STEM careers more broadly. We also believe that science is better when it includes different perspectives and voices. We strive to make the Allen Institute a place where everyone feels like they belong and are empowered to do their best work in a supportive environment. We are an equal-opportunity employer and strongly encourage people from all backgrounds to apply for our open positions.

Requirements

Bachelors degree in life sciences (e.g., Neuroscience, Molecular Biology, Biochemistry, Cell Biology, or related field) or computational biology
2 years of related experience
Experience preparing biological samples (tissues, cells) for LC-MS analysis, including protein extraction, digestion, sample clean-up and using various enrichment techniques (e.g., precipitation) to enhance detection sensitivity
Experience with standard molecular biology techniques, including cloning, cell/nuclei isolation, and PCR

Nice To Haves

Positive attitude, self-motivated, and ability to troubleshoot
Experience in histological methods such as tissue sectioning and staining
Experience in computational analysis of proteomics and/or genomics data
Experience with handling large, complex data set analysis using R, Python, and/or Linux shell scripting
Familiarity with cloud computing environments

Responsibilities

This is primarily a lab-based position focused on performing a variety of proteomics workflows, including cell-based and biochemical assays focused on the generation of samples
Collaborate with team members to perform proteomics experiments, including the testing and optimization of methods for cell type-specific proteomics experiments
Show willingness to learn new protocols, relevant equipment, related software, and data analysis methods
Summarize and present data in both oral and written formats and prepare data for sharing with internal and external collaborators

Benefits

Employees (and their families) are eligible to enroll in benefits per eligibility rules outlined in the Allen Institutes Benefits Guide.
These benefits include medical, dental, vision, and basic life insurance.
Employees are also eligible to enroll in the Allen Institutes 401k plan.
Paid time off is also available as outlined in the Allen Institutes Benefits Guide.
Details on the Allen Institutes benefits offering are located at the following link to the Benefits Guide:

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