Research Associate II/III, In Vivo

Crown Bioscience•Kannapolis, NC

About The Position

Job Summary: The purpose of the In Vivo Research Associate II/III position is to independently conduct in vivo studies in support of the Company's goals and objectives. Responsibilities: - Works closely with Study Directors, Study Coordinators and cross functional team members to ensure all assigned studies are conducted in accordance with study protocols, standard operating procedures and company policies - Collection of body weight data - Collection of tumor volume measurements - Collect tissue samples and process for shipment to sponsor as well as internal purposes - Responsible for the tracking of samples and shipping of samples to sponsor companies - Preparation of animals for procedures, including shaving, ear tagging and other tasks as directed - Performance of clinical observations and humane euthanasia in mice - Collect relevant data and provide feedback to team members regarding progress of assigned projects - Perform advanced in vivo procedures (including sample collection, surgeries.) with minimal direct supervision required - May be trained on more complex procedures - Perform subcutaneous inoculations - Administer therapeutic agents through different routes of administration, including IP, PO, SC, IM, ID, IN and IV - Providing general group support by cleaning, general supply stocking and sample shipping - Responsible for tracking time spent on projects (project logs) Minimum Requirements: - Bachelor's degree is required - 2-3 years of experience handling animals in a Vivarium environment is required - Comfortable working in a laboratory animal research environment - Demonstrated ability to perform a minimum of three of the following in vivo oncology tumor models in mice: - Animal handling - Tumor implantation - Tumor measurement - Gross necropsy - Simple drug preparation - Drug administration by various routes - Minor survival surgery - In-life and terminal bleeds - Demonstrated sense of integrity and confidentiality - Planning, organizational skills and flexibility in a reactive environment - Demonstrated accountability and responsibility for own work - Ability to follow standard operating procedures, observe safety and security procedures - Able to troubleshoot effectively and solve problems with supervision Preferred Requirements: - AALAS certification at ALAT level or higher is preferred Crown Bioscience is committed to a diverse and inclusive workplace. Crown Bioscience is an equal opportunity employer and does not discriminate based on race, national origin, gender, gender identity, sexual orientation, protected veteran status, disability, age, or other legally protected status. Crown Bioscience, a JSR Life Sciences company, is a global contract research organization (CRO) providing discovery, preclinical, and translational platforms to advance oncology and immuno-oncology. Known for their high quality and expansive in vivo, in vitro, and ex vivo preclinical models, they partner with their clients to quantify the efficacy and pharmacological profile of their drug candidate before they move into the clinic. The company is the only preclinical CRO to provide tumor organoid services utilizing HUB technology and has the world’s largest commercially available PDX collection. Additionally, further services available in the areas of high content imaging and a 3D Ex Vivo Patient Tissue Platform, provide greater insights into complex disease pathophysiology. A range of biomarker analysis and applied genomics services are also available to optimize therapeutic benefit. Crown Bioscience helps to deliver superior drug candidates to ensure that patients get the right treatment at the right time. Founded in 2006, Crown Bioscience has 12 facilities in the US, Europe, and APAC. Find out more: www.crownbio.com Crown Bioscience is committed to a diverse and inclusive workplace. Crown Bioscience is an equal opportunity employer and does not discriminate on the basis of race, national origin, gender, gender identity, sexual orientation, protected veteran status, disability, age, or other legally protected status. If you have a disability or special need that requires accommodation, please let us know: [email protected] Headhunters and recruitment agencies may not submit resumes/CVs through this website or directly to managers. Crown Bioscience does not accept unsolicited headhunter and agency resumes. Crown Bioscience will not pay fees to any third-party agency or company that does not have a signed agreement with Crown Bioscience.

Requirements

Bachelor's degree is required
2-3 years of experience handling animals in a Vivarium environment is required
Comfortable working in a laboratory animal research environment
Demonstrated ability to perform a minimum of three of the following in vivo oncology tumor models in mice:
Animal handling
Tumor implantation
Tumor measurement
Gross necropsy
Simple drug preparation
Drug administration by various routes
Minor survival surgery
In-life and terminal bleeds
Demonstrated sense of integrity and confidentiality
Planning, organizational skills and flexibility in a reactive environment
Demonstrated accountability and responsibility for own work
Ability to follow standard operating procedures, observe safety and security procedures
Able to troubleshoot effectively and solve problems with supervision

Nice To Haves

AALAS certification at ALAT level or higher is preferred

Responsibilities

Works closely with Study Directors, Study Coordinators and cross functional team members to ensure all assigned studies are conducted in accordance with study protocols, standard operating procedures and company policies
Collection of body weight data
Collection of tumor volume measurements
Collect tissue samples and process for shipment to sponsor as well as internal purposes
Responsible for the tracking of samples and shipping of samples to sponsor companies
Preparation of animals for procedures, including shaving, ear tagging and other tasks as directed
Performance of clinical observations and humane euthanasia in mice
Collect relevant data and provide feedback to team members regarding progress of assigned projects
Perform advanced in vivo procedures (including sample collection, surgeries.) with minimal direct supervision required
May be trained on more complex procedures
Perform subcutaneous inoculations
Administer therapeutic agents through different routes of administration, including IP, PO, SC, IM, ID, IN and IV
Providing general group support by cleaning, general supply stocking and sample shipping
Responsible for tracking time spent on projects (project logs)