Research Associate-Fixed Term
About The Position
The Research Associate (post-doc) will join a research lab focused on understanding the role of the tau protein in neurodegeneration and developing novel therapeutics for diseases such as Alzheimer's disease and other tauopathies. The applicant will help carry out and develop research projects to understand the mechanisms involved in the development and progression of these diseases as well as develop novel gene therapies using a variety of techniques and model systems. The position will involve work with rodent models, cell culturing, and in vitro experimental techniques. The experimental duties may include rodent handling and husbandry, harvesting and culturing primary neurons, gene therapy approaches, Western blotting, DNA cloning, culturing of cell lines, fresh and fixed tissue processing, immunostaining, and other biochemical and molecular techniques. The applicant will take a leading role in collecting and analyzing data as well as writing manuscripts publication. This is an opportunity to grow and develop important skills necessary for career progression. The position is in the laboratory of Dr. Nicholas Kanaan in the highly collaborative and innovative Department of Translational Neuroscience, located at the MSU Grand Rapids Research Center, 400 Monroe Ave NW, Grand Rapids, MI.
Requirements
- Doctoral degree (or equivalent) in a scientific field, preferably molecular biology, neuroscience, or a related field with multiple years of experience in a research laboratory
- Experience performing basic research techniques in the specific or related field as well as a fundamental understanding of molecular and cellular biology as well as neuroscience
- Detail oriented and self-motivated with the ability to independently carry out research and must interact, communicate, and work well with others
- Demonstrated record of publishing high quality research and have experience with statistical analysis of data
Nice To Haves
- Experience/training in neuroscience and/or neurodegenerative disease research, gene therapy approaches, or intracellular signaling pathways are strongly desired
- Rodent (mice and/or rats) handling experience. This includes animal husbandry (colony maintenance and genotyping), carrying out and analyzing behavioral experiments, intracerebral surgery/delivery, AAV use, necropsy and post-mortem tissue processing
- Advanced microscopy including confocal, brightfield/fluorescence, and transmission electron microscopy
- Advanced gene and protein analysis (e.g. SDS-PAGE, Western blotting, ELISA, MSD, immunohistochemistry, immunofluorescence, ddPCR/qRT-PCR
- Statistical analysis of data
Responsibilities
- Carry out and develop research projects
- Understand the mechanisms involved in the development and progression of neurodegenerative diseases
- Develop novel gene therapies
- Work with rodent models, cell culturing, and in vitro experimental techniques
- Rodent handling and husbandry
- Harvesting and culturing primary neurons
- Gene therapy approaches
- Western blotting
- DNA cloning
- Culturing of cell lines
- Fresh and fixed tissue processing
- Immunostaining
- Other biochemical and molecular techniques
- Collecting and analyzing data
- Writing manuscripts publication
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
Industry
Educational Services
Education Level
Ph.D. or professional degree
Number of Employees
5,001-10,000 employees
