Process Development Co-op (Fall 2026)

Wave Life Sciences•Lexington, MA

About The Position

Wave Life Sciences is a biotechnology company focused on unlocking the broad potential of RNA medicines to transform human health. Our RNA medicines platform, PRISM, combines multiple modalities, chemistry innovation and deep insights in human genetics to deliver scientific breakthroughs that treat both rare and prevalent disorders. Our toolkit of RNA-targeting modalities includes editing, splicing, RNA interference and antisense silencing, providing us with unmatched capabilities for designing and sustainably delivering candidates that optimally address disease biology. Our diversified pipeline includes clinical programs in Duchenne muscular dystrophy, Alpha-1 antitrypsin deficiency and Huntington’s disease, as well as a clinical program in obesity and a preclinical program in NASH/MASH. Driven by the calling to “Reimagine Possible”, we are leading the charge toward a world in which human potential is no longer hindered by the burden of disease. Wave Life Sciences USA seeks a highly motivated co-op students to join its team of scientists in Lexington, Massachusetts. The co-op student will gain exposure to areas of oligonucleotide synthesis, purification, and analysis. Co-ops will be trained in a variety of laboratory techniques and instrumentation, making this an excellent learning opportunity. This is an ideal position for any student, including those looking for their first co-op, with strong organizational skills and attention to detail who thrives in a team-oriented, fast-paced and cross-disciplinary biotech environment. Organic chemistry or biochemistry laboratory experience is preferred.

Requirements

strong organizational skills
attention to detail
thrives in a team-oriented, fast-paced and cross-disciplinary biotech environment

Nice To Haves

Organic chemistry or biochemistry laboratory experience

Responsibilities

Assist in the upstream and downstream development of oligonucleotides
Preparation of synthesis reagents for solid phase oligonucleotide synthesis by weighing organic compounds and preparing reagents
Independently prepare buffer solutions of specified molarity for purification of oligonucleotides
Assist in the operation of AKTA systems and be able to learn and work on UNICORN software
Assist in running desalting operations on Sartoflow TFF systems
Prepare and submit samples on analytical systems such as UPLC and LCMS and conduct analysis
Maintain a detailed report of experimental procedures and findings in electronic lab notebooks
Use of pH meter, Nanodrop to record data
Use of MS Excel is preferred
Present experimental data in team meetings
Eager to learn about instrumentation and work with new technology
Following the lab safety protocols including use of PPEs