Process Chemistry Principal Scientist

Vertex Inc. • Boston, MA

1d • $138,000 - $207,000 • Onsite

About The Position

General Summary: The Process Chemistry Principal Scientist is technically self-reliant with an extensive track record of accomplishments and will identify and solve complex problems repeatedly across a number of critical and diverse projects. This role will serve as an emerging technical expert in the field and provide reliable and valuable advice to project teams on a regular basis.

Requirements

• Ability and track record of successfully working in cross-functional teams.
• Experience in drafting, reviewing and submitting required documentation pertaining to the development and preparation of drug substances under cGMP environment
• In-depth conceptual knowledge of SOPs and GMPs and ensure compliance with all applicable regulations and SOPs.
• Experience in writing and transferring developed technology to outside CROs and working with suppliers to solve chemical issues for compound delivery.
• Excellent verbal and written communication skills to explain difficult or sensitive technical/scientific information and to prepare presentations and reports
• Bachelor's degree in relevant field
• Bachelor's degree and 10+ years of experience or a Master's degree and 7+ years of experience or a PhD and 4-7 years of experience, or the equivalent combination of education and experience

Nice To Haves

• Experience and ability to draft CMC sections of INDs or CTAs is a plus.

Responsibilities

• Designs and performs sophisticated, technically challenging experiments, efficiently and independently ensuring compliance with applicable regulations and SOPs
• Generates effective hypotheses to pursue project goals and sets new experimental direction
• Identifies broad implications of results and their impact on overall study
• Develops novel and creative solutions to overcome project obstacles
• Makes substantive conceptual contributions to project activities and scientific strategies
• Provides authoritative technical recommendations broadly within the company regarding own discipline and occupies a key or pivotal formal or informal project role
• Serves as a practical manager of CRO interactions and external collaboration

Benefits

• This role is eligible for an annual bonus and annual equity awards.
• Some roles may also be eligible for overtime pay, in accordance with federal and state requirements.
• At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.
• From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

What This Job Offers

• Job Type: Full-time
• Career Level: Principal