Principal Scientist, Chemical Development

Neurocrine Biosciences • San Diego, CA

1d

About The Position

Responsible for research and development, tech transfer and commercialization of drug substance processes, as well as oversight of batch manufacturing and regulatory document contribution through managerial and individual input. Provides project management for CMC programs or Chemical Development projects. Manages direct reports.

Requirements

• BS/BA in chemistry and 12+ years of experience in experience in pharmaceutical/process development field, including API manufacturing person in plant activities, Experience managing laboratory, maximizing productivity is desirable OR MS/MA in chemistry and 10+ years of similar experience noted above OR PhD in chemistry and 4+ years of similar experience noted above; may include postdoc experience OR
• Thorough understanding of organic chemistry and a well-developed understanding of process chemistry as well as current literature
• Excellent laboratory and productivity skills
• API Manufacturing experience
• Good understanding of cGMP requirements in API
• Demonstration of cross-functional understanding related to drug development
• Assimilates data and research findings outside of Neurocrine for application to new scientific projects
• Maintains broad knowledge of scientific principles and theories and possesses intellectual mastery of one or more scientific areas
• May develop an understanding of other areas and related dependencies
• Advanced knowledge and demonstrated ability working with / recommending a variety of laboratory equipment/tools
• Ability to work as part of and lead multiple teams
• Exhibits leadership skill and ability, typically leads lower levels and/or indirect teams
• Excellent computer skills
• Excellent interpersonal, communications, problem-solving, analytical thinking skills
• Sees broader picture, impact on multiple programs, teams and/or departments
• Ability to meet multiple deadlines across a variety of projects/programs, with a high degree of accuracy and efficiency
• Excellent project management skills
• Neurocrine Biosciences is an EEO/Disability/Vets employer. We are committed to building a workplace of belonging, respect, and empowerment , and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don’t line up to exactly what we have outlined in the job description.

Responsibilities

• Plans and manages projects.
• Represents Chemical Development on cross-functional teams.
• Maintains accountability for deliverables and progress on R&D and manufacturing plans for Chemical Development projects
• Independently designs, plans and executes activities towards the goals of one or more Chemical Development projects to support preclinical through commercial activities
• Supervises laboratory work and/or lab personnel and ensures safe laboratory practices
• Performs process R&D and optimizes synthetic routes
• Identifies and recommends approaches to novel ideas in Chemical Development
• Provides support for off-site synthesis, manufacturing activities and interaction with contractors
• Provides input into CMC regulatory documentation and supporting work
• May provide supervision of laboratory personnel and guidance for their professional development
• Contributes to development of policies and executes against department strategies
• Builds and enhances internal and external professional relationships
• Other duties as assigned

Benefits

• retirement savings plan (with company match)
• paid vacation, holiday and personal days
• paid caregiver/parental and medical leave
• health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Number of Employees: 1,001-5,000 employees